Abstract:OpinionChronic Rhinosinusitis (CRS) is defined as inflammation of the mucosa lining the paranasal sinuses that lasts more than 12 weeks. Patients with CRS are classified into two subtypes: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP) [1,2]. However, recent evidences indicate that the inflammation reaches beyond the mucosa of the sinus reaching the underlying bones as part of the disease process. Moreover, accumulating evidences indicate the involvement of special molecular events in pat… Show more
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