Chronic recurrent multifocal osteomyelitis causing spinal cord compression

Baulot, E.; Bouillien, D.; Giroux, Eric-Alban; Grammont, P

doi:10.1007/s005860050085

Cited by 29 publications

(22 citation statements)

References 17 publications

(32 reference statements)

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“…Spinal disease may be detected incidentally during the radiologic work-up of suspected CRMO, or it may be the site of primary presentation. Presenting symptoms can include back pain, scoliosis or kyphosis, and rarely cord compression (59).…”

Section: Spinementioning

confidence: 99%

Imaging of Chronic Recurrent Multifocal Osteomyelitis

Khanna¹,

Sato²,

Ferguson³

2009

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Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disorder of children and young adults that is characterized by nonbacterial osteomyelitis. Patients typically present with multifocal bone pain secondary to sterile osseous inflammation, and the disease has a relapsing and remitting course. The cause of CRMO remains unclear, although the results of several studies have suggested a genetic component. The typical imaging findings of CRMO include lytic and sclerotic lesions in the metaphyses of long bones and the medial clavicles. Other common sites of disease are the vertebral bodies, pelvis, ribs, and mandible. CRMO is often bilateral and multifocal at presentation. Owing to the lack of a diagnostic test, CRMO remains a diagnosis of exclusion. Although generally a self-limiting disease, CRMO can have a prolonged course and result in significant morbidity. Radiologists can be the first to suggest this diagnosis given its characteristic radiographic appearance and distribution of disease. Radiologists should be familiar with the typical imaging findings of CRMO to prevent unnecessary multiple biopsies and long-term antibiotic treatment in children with CRMO.

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Section: Spinementioning

confidence: 99%

Imaging of Chronic Recurrent Multifocal Osteomyelitis

Khanna¹,

Sato²,

Ferguson³

2009

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312

285

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“…21,22 All authors agree with the recommendation that CRMO patients be monitored closely for severe complications so that effective treatment can be started early. Operative treatment should be avoided as much as possible.…”

Section: Discussionmentioning

confidence: 69%

Chronic recurrent multifocal osteomyelitis presenting as pseudoseptic sacroiliac joint arthritis: a case report and review of literature

El-Zayat¹,

Efe²,

Fuchs-Winkelmann³

et al. 2010

Current Orthopaedic Practice

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“…Detecting the presence of more than one focus, and in particular of foci that are symmetrically situated in the bone system, suggests the diagnosis of CRMO in no uncertain terms [2,10]. In turn, detection of radiologically active foci in the vertebral bodies is an indication for implementing CRMO therapy and allows avoidance of complications associated with clinical activation of foci [9,11,12].…”

Section: Discussionmentioning

confidence: 99%

Comparison of results of whole-body magnetic resonance imaging scans and traditional imaging modalities in diagnostic management of chronic recurrent multifocal osteomyelitis

Sułko¹,

Oberc²

2018

Arch Med Sci Civil Dis

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Introduction: The diagnosis of chronic recurrent multifocal osteomyelitis (CRMO) is frequently the result of excluding other diseases. The only methods that provide images of the multicentricity of radiologically active foci are whole body bone scintigraphy (SCI) and whole body MRI (WBMRI). The objective of the study was to compare the results of WBMRI and traditional imaging modalities in CRMO. Material and methods: The study group consisted of 20 children with the mean age of 9.5 years. WBMRI imaging was performed between June and December of 2014. The mean follow-up period after completion of the study was 35 months. All the patients included in the study were additionally subjected to examination of clinically active CRMO foci by computed tomography, classic radiographic diagnostic management and scintigraphy. Results: All the patients manifested clinically active foci. In the group of the investigated patients, the highest number of foci in concordance with the clinical picture was noted in SCI-29, followed by CT-22 and WBMRI-21, while plain X-ray yielded the lowest number of positive results-12. Conclusions: The results of the present study do not confirm the highest sensitivity of WBMRI in determining possible disease foci in CRMO as compared to other imaging modalities. Higher sensitivity in detection of radiologically active foci in CRMO was noted in bone system scintigraphy. During the 35-month follow-up, none of the WBMRI-detected radiologically active and clinically silent foci underwent clinical activation.

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Chronic recurrent multifocal osteomyelitis causing spinal cord compression

Cited by 29 publications

References 17 publications

Imaging of Chronic Recurrent Multifocal Osteomyelitis

Imaging of Chronic Recurrent Multifocal Osteomyelitis

Chronic recurrent multifocal osteomyelitis presenting as pseudoseptic sacroiliac joint arthritis: a case report and review of literature

Comparison of results of whole-body magnetic resonance imaging scans and traditional imaging modalities in diagnostic management of chronic recurrent multifocal osteomyelitis

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