2004
DOI: 10.1089/089277904773582804
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Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Is There a Role for Local Drug Infiltration Therapy?

Abstract: The clinical syndrome of chronic prostatitis ranges from well-defined chronic bacterial infections to poorly defined chronic pelvic pain syndrome (CPPS), previously referred to as "prostatodynia" or "abacterial prostatitis." Faced with the obscure nature of the disease, its protracted course, and the poor response to oral medication, urologists have considered alternative routes of drug administration. We review the indications and outcomes of local drug infiltration (intraprostatic antibiotic and zinc, intras… Show more

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Cited by 13 publications
(8 citation statements)
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References 27 publications
(17 reference statements)
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“…Many treatment protocols have been assessed previously, e.g., a-blocker therapy and antimicrobial therapy, but have failed to provide an acceptable outcome [15][16][17][18][19][20][21], and the search for other drug regimens for such patients has gained favour among physicians [22,23].…”
Section: Discussionmentioning
confidence: 99%
“…Many treatment protocols have been assessed previously, e.g., a-blocker therapy and antimicrobial therapy, but have failed to provide an acceptable outcome [15][16][17][18][19][20][21], and the search for other drug regimens for such patients has gained favour among physicians [22,23].…”
Section: Discussionmentioning
confidence: 99%
“…A suppressive effect of BoNT-A on smooth muscle tone and sensory neurons, along with atrophy of the prostate gland induced by intraprostatic injection of BoNT-A, may be important mechanisms in relieving LUTS [10][11][12][13][14][15][16][17].…”
Section: Discussionmentioning
confidence: 99%
“…The management of refractory CP/CPPS is frustrating and disappointing both for patients and physicians. Many treatment protocols have been assessed previously, e.g., α-blocker therapy and antimicrobial therapy, but have failed to provide an acceptable outcome [15–21] , and the search for other drug regimens for such patients has gained favour among physicians [22,23] .…”
Section: Discussionmentioning
confidence: 99%