Chronic Proliferative Lesions of the Urinary Tract

Stirling, Calhoun; Ash, J.E.

doi:10.1016/s0022-5347(17)71060-9

Cited by 68 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cystitis cystica nodules contain lymphoid cells 6,7 and have often been considered as variations of normal, premalignant lesions, or nonspecific responses to chronic inflammation. 5,[8][9][10][11] In pediatric patients, the number of bladder nodules seen on cystoscopy has been found to correlate with the number of UTI episodes in the preceding year, 7 possibly suggesting that bladder nodules increase the risk of UTIs in younger patients. However, no studies, to our knowledge, have investigated the relationship between bladder nodules or CC and UTI incidence in adult women.…”

mentioning

confidence: 99%

Recurrent Urinary Tract Infection Incidence Rates Decrease in Women With Cystitis Cystica After Treatment With d-Mannose: A Cohort Study

Chiu

Zhang

Sutcliffe

et al. 2022

Female Pelvic Med Reconstr Surg

View full text Add to dashboard Cite

Objectives: D-Mannose is a promising nonantibiotic prophylaxis for recurrent urinary tract infection (rUTI). Recurrent UTI is common in postmenopausal women and may be especially prevalent in those with cystitis cystica (CC) lesions found on cystoscopy. Our objectives were to determine whether CC lesions are associated with a higher UTI incidence rate and whether D-mannose reduces this rate in women with CC.Methods: This is a retrospective cohort study of patients with rUTI who underwent cystoscopy at our institution (from which CC status was identified) and who were treated with D-mannose as a single agent for UTI prophylaxis. Participants were required to have at least 1 year of follow-up for UTIs both before and after D-mannose initiation to allow for a pre-post comparison.Results: Twenty-seven patients were included in the analysis (13 with CC, 14 without CC). Most patients (88.9%) were postmenopausal. Patients with CC had a higher UTI incidence rate than patients without CC (4.69 vs 2.93 UTIs/year before starting D-mannose prophylaxis, P = 0.021). After initiating D-mannose prophylaxis, the UTI incidence rate decreased significantly in patients with CC (rate decrease = 2.23 UTIs/year, P = 0.0028). This decrease was similar in magnitude to that observed in patients without CC (rate decrease = 1.64 UTIs/year, P = 0.0007; P interaction = 0.58).Conclusions: Patients with rUTI with CC had more frequent UTI episodes than patients without CC. Patients in both groups had fewer UTI episodes after beginning D-mannose prophylaxis. These findings add to the body of literature supporting D-mannose for the prevention of rUTI in women, including those with CC.

show abstract

mentioning

confidence: 99%

Recurrent Urinary Tract Infection Incidence Rates Decrease in Women With Cystitis Cystica After Treatment With d-Mannose: A Cohort Study

Chiu

Zhang

Sutcliffe

et al. 2022

Female Pelvic Med Reconstr Surg

View full text Add to dashboard Cite

show abstract

“…Some authors have thought them normal (Hamburger, 1879;Weischselbaum, 1881;Alexander, 1893;Asschoff, 1894;and Bohm and Von Davidoff, 1895) but Chiari (1881) and Przewoski (1889) believed that they signified infection. This is implied in the term 'cystitis follicularis', used to denote subepithelial lymphoid follicles and considered by some to be a common sequel to prolonged urinary infection (Hinman and Cordonnier, 1935;Stirling and Ash, 1941). However, Kretschmer (1952) believed that infection was common, but follicular changes were rare.…”

Section: Discussionmentioning

confidence: 99%

The relationship between urinary infection, cystoscopic appearance, and pathology of the bladder in man

Marsh¹,

Banerjee²,

Panchamia³

1974

J Clin Pathol

View full text Add to dashboard Cite

show abstract

“…Longstanding urinary infection has been considered an important predisposing factor (Heymann, 1905;Stirling and Ash, 1941;Connery, 1953;Abeshouse and Tankin, 1956;Politano, 1956;Holley and Mellinger, 1961;Smith, Webb, and Price, 1962;Clarke and Gherardi, 1962;Streitz, 1963;O'Flynn and Mullaney, 1967), a view which has experimental support (Ball, Field, Roe, and Walters, 1964). It is also widely believed to be precarcinomatous (Politano, 1956;Holley and Mellinger, 1961;Roe, 1964;Ball et al, 1964;O'Flynn and Mullaney, 1967).…”

Section: Discussionmentioning

confidence: 99%

The relationship between urinary infection, cystoscopic appearance, and pathology of the bladder in man

1974

J Clin Pathol

View full text Add to dashboard Cite

The occurrence of squamous change in the bladder epithelium was studied in bladder biopsies from patients with recurrent urinary infections or symptoms of cystitis and comparisons were made with sections taken at necropsy from control subjects. Two types of squamous change, termed `vaginal' and `cornified', are described. Vaginal change was frequent in females, and seemed to be a normal finding in them, but was not observed in males. It did not seem to be caused by urinary infection. Cornified change was also common in females and was found in one (infected) man. Like vaginal change it was most often found in sections from the trigone. Urinary infection may predispose to its formation but we were unable to prove this. Squamous change did not seem to cause symptoms, and could not usually be recognized at cystoscopy. The varieties described are so common that they are unlikely to be markedly precarcinomatous.

show abstract

Chronic Proliferative Lesions of the Urinary Tract

Cited by 68 publications

References 21 publications

Recurrent Urinary Tract Infection Incidence Rates Decrease in Women With Cystitis Cystica After Treatment With d-Mannose: A Cohort Study

Recurrent Urinary Tract Infection Incidence Rates Decrease in Women With Cystitis Cystica After Treatment With d-Mannose: A Cohort Study

The relationship between urinary infection, cystoscopic appearance, and pathology of the bladder in man

The relationship between urinary infection, cystoscopic appearance, and pathology of the bladder in man

Contact Info

Product

Resources

About