Chronic progressive lymphoedema in draught horses

Abstract

The objective of this review was to summarise and evaluate the current state of knowledge about chronic progressive lymphoedema in draught horses. Clinical signs of this multifactorial disorder are mainly restricted to the lower limbs, comprising progressively deteriorating skin, swelling and deformation. Although typical lesions were first reported at the beginning of the 20th century, chronic progressive lymphoedema was recognised as a specific syndrome only in 2003, and since then research has driven forward. Despite the high prevalence in some breeds and the serious economic impact, the pathogenesis is not fully understood, and the available treatment options remain symptomatic and noncurative. There is a need to improve diagnostic techniques and to develop selection tools.

Chronic progressive lymphoedema in Friesian horses: suggestive phenotype of affected horses and genome‐wide association study

“…Chronic progressive lymphoedema (CPL) is a disorder affecting the lymphatic system with clinical manifestation in the lower legs of many draft horse breeds, including Shires, Belgian draft horses, Clydesdales, gypsy vanners, some German draft breeds as well as Friesian horses . Clinical signs may occur from as early as two years of age .…”

Effects of compression bandages and a protection boot on sub-bandage pressure and lymph flow on the distal equine limb

“…Auch in der Literatur wird Bewegung als Lymphabflussfördernd beschrieben (Ratzlaff et al 1985, Rötting et al 2000, Siewert et al 2011, Keyser et al 2015. Weitere Untersuchungen zu den Druckverhältnissen in der Bewegung sind daher von großem Interesse und sollten auch mit dem hier beschriebenen Messsystem über 16 Sensoren und den genutzten Kompressionsbandagen erfolgen.…”

“…Üblicherweise werden dann Stallbandagen angelegt, um eine Reduzierung der Ödeme durch Kompression zu erreichen (Rötting et al 2000, Keyser et al 2015. Weitere Therapiemöglichkeiten sind Bewegung (Rötting et al 2000, Siewert et al 2011, Keyser et al 2015 und manuelle Lymphdrainage (Rötting et al 2000).…”

“…Üblicherweise werden dann Stallbandagen angelegt, um eine Reduzierung der Ödeme durch Kompression zu erreichen (Rötting et al 2000, Keyser et al 2015. Weitere Therapiemöglichkeiten sind Bewegung (Rötting et al 2000, Siewert et al 2011, Keyser et al 2015 und manuelle Lymphdrainage (Rötting et al 2000). Allerdings konnte in einer Studie mit 10 Pferden eine Unterbrechung des Lymphflusses durch eine übliche Bandagierung (Wollbandage und Unterleger) festgestellt werden (Fedele et al 2006).…”

Pneumatic compression therapy using the EQ Press accelerates lymphatic flow in healthy equine forelimbs as determined by lymphoscintigraphy

“…Peripheral lymphedema in the horse can be the manifestation of a variety of primary disease processes, including lymphangitis, cellulitis, vasculitis or venous congestion, hypoalbuminemia, and congestive heart failure, 1 or a result of breed predilection, such as chronic progressive lymphedema (CPL) in draught breeds. [2][3][4][5] Many of these can be devastating life-long disorders in which inadequate lymphatic drainage or excessive lymph fluid accumulation of…”