Chronic peritoneal dialysis in children

Fraser, Nia; Hussain, Farida; Connell, Roy; Shenoy, Manoj

doi:10.2147/ijnrd.s82419

Cited by 30 publications

(29 citation statements)

References 56 publications

(62 reference statements)

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“…PD-related peritonitis has decreased since the late 1980s; however, peritonitis remains the major complication of PD and the most common reason for changing dialysis modality [1, 5-7]. According to Standardizing Care to Improve Outcomes in Pediatric end-stage renal disease Collaborative, the global peritonitis incidence rate is 0.46 episodes per patient-year [8], while the North American Pediatric Renal Transplant Cooperative Study found 0.68 peritonitis episodes per patient-year in PD-treated children [9].…”

Section: Introductionmentioning

confidence: 99%

Peritonitis in Children on Chronic Peritoneal Dialysis: The Experience of a Large National Pediatric Cohort

Ponce¹,

Pécoits-Filho²,

Figueiredo³

et al. 2017

Blood Purif

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Background: We performed this study to evaluate the incidence, risk factors, microbiology, treatment, and outcome of peritonitis in pediatric Peritoneal dialysis (PD) patients at a nationwide prospective study. Methodology: Patients younger than 18 years recruited in the BRAZPD II study from 2004 to 2011, who presented their first peritonitis episode, were included in the study. Results: We found 125 first episodes of peritonitis in 491 children PD patients (0.43 episodes/patient-year). Patients free of peritonitis episode constituted 75.6% in 1 year. Culture-negative episodes were very high (59.2%) and gram-positive (GP) bacteria were the most commonly found organisms (58.8%). First-generation cephalosporin was the initial choice to cover GP (40.5%) and aminoglycosides was the most prescribed antibiotics used for gram-negative agents (27.5%). Treatment failure was 26.4%. Technique failure (TF) occurred in 12.1% and peritonitis was the main cause (65.1%). Pseudomonas (p = 0.04) and negative cultures (p < 0.001) were identified as predictors of TF. Conclusion: Peritonitis remains a common complication of PD in children and negative cultures and pseudomonas had a negative impact on TF.

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Section: Introductionmentioning

confidence: 99%

Peritonitis in Children on Chronic Peritoneal Dialysis: The Experience of a Large National Pediatric Cohort

Ponce¹,

Pécoits-Filho²,

Figueiredo³

et al. 2017

Blood Purif

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“…Peritonitis is known to be a commonest complication of PD in many national 14,16 and international studies. 19,20 Catheter related complications are also very common in children undergoing PD. 11,15 Higher rates of peritonitis in comparison to present work have also been reported earlier.…”

Section: Discussionmentioning

confidence: 99%

Outcome of acute peritoneal dialysis (APD) in renal failure among children admitted at Children’s Hospital and Institute of Child Health, Multan.

Ishaq

Joiya

Khan

2020

TPMJ

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Objectives: Renal failure (RF) is associated with significant mortality and morbidity. its management still remains challenging for treating physicians. Acute peritoneal dialysis (APD) is an option for treatment of renal failure among young children. We aimed to determine the efficacy of peritoneal dialysis (PD) in RF among children admitted. Study Design: Case series study. Setting: Nephrology Department of Children’s Hospital and Institute of Child Health, Multan. Period: February 2018 to July 2018. Material & Methods: A total of 74 children with renal failure were included. All the patients were treated with acute peritoneal dialysis. The outcome of interest was clinical and biochemical improvement. Result: Amongst all there were 46 (62.2%) male and 26 (37.8%) female. Mean age of the children was found to be 57.72 months. Mean weight of children was 12.36 kg with a standard deviation of 6.4 kg. Most of the children, 43 (58.1%) had acute renal failure (ARF) whereas 31 (41.9%) had chronic renal failure (CRF). With PD, mortality was reported in 22 (29.7%) children. Conclusion: Acute peritoneal dialysis showed good rates of improvement in renal function, so, it should be recommending among children with acute renal failure.

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“…Rates of peritonitis are also significantly higher. A 25-year study of infant dialysis reports an odds ratio of 19 ( p < 0.001) for peritonitis in patients with concurrent gastrostomies (12). Fungal peritonitis, although observed to be higher, was not statistically significant (13).…”

Section: Discussionmentioning

confidence: 99%

Laparoscopic Peritoneal Dialysis Catheter Placement with Chest Wall Exit Site for Neonate with Stoma

Saxena

Badru

et al. 2019

Perit Dial Int

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Neonates requiring peritoneal dialysis (PD) catheters have been shown to have complication rates up to 70%. The presence of a concurrent stoma significantly increases the risk of peritonitis, exit-site infection, and catheter failure. As such, multiple techniques have been proposed to reduce these risks, including a chest wall exit site. In this case, the patient was born with bilateral hypoplastic kidneys and an anorectal malformation, requiring a colostomy soon after birth. At 4 weeks of life, he required placement of a PD catheter for dialysis. Given the high risk of infection, a laparoscopic-assisted PD catheter placement with a chest wall exit remote from the colostomy was performed. This report describes the operative technique including omentectomy, placement of a percutaneous stitch between the catheter cuffs, and fibrin glue injection around the catheter. The patient had no catheter-related infections. Laparoscopic-assisted PD catheter placement with chest wall exit site is a safe alternative in patients with any type of abdominal stoma.

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Chronic peritoneal dialysis in children

Cited by 30 publications

References 56 publications

Peritonitis in Children on Chronic Peritoneal Dialysis: The Experience of a Large National Pediatric Cohort

Peritonitis in Children on Chronic Peritoneal Dialysis: The Experience of a Large National Pediatric Cohort

Outcome of acute peritoneal dialysis (APD) in renal failure among children admitted at Children’s Hospital and Institute of Child Health, Multan.

Laparoscopic Peritoneal Dialysis Catheter Placement with Chest Wall Exit Site for Neonate with Stoma

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