Chronic pain associated with malignant neoplasm. Modern terms and classification

Abstract

According to 2019 data, the incidence of cancer in Russia increases by 1.5% annually, 8.5 million people die from malignant neoplasms. Pain is the most common symptom when diagnosed with a malignant neoplasm. In the final stage of the disease, about 66% of patients experience pain, and in most cases the intensity of pain syndrome is regarded as moderate to severe pain. In the international classification of diseases 11 revisions (μb-11), the diagnosis of chronic pain is supposed to be reflected in a separate section. The aim of the review was to present a modern classification of chronic pain associated with malignancy. The search for publications has been carried out by two independent researchers since 01.2010. until 12.2020. in the databases PubMed, MEDLINE, EMBASE, Cochrane, as well as the International Association for the Study of Pain. The International Association for the Study of Pain has established a special group, which, in close collaboration with WHO representatives, has developed a new classification of chronic pain. Chronic pain caused by malignancy: chronic visceral pain caused by malignancy; chronic bone pain caused by malignancy; chronic neuropathic pain caused by malignancy; other chronic pain caused by malignancy. Chronic pain due to treatment of malignant neoplasm: chronic pain caused by drug treatment of malignant neoplasm Chronic polyneuropathy due to chemotherapy; chronic pain caused by radiation therapy of malignant neoplasm; chronic neuropathy due to radiation therapy; Chronic pain caused by surgical treatment of malignant neoplasm. Other chronic pain caused by treatment of malignant neoplasm. Thus, the inclusion in the MKB-11 of a separate classification of chronic pain associated with malignancy will lead to the correct formulation of the diagnosis, which will contribute to individualized treatment (antitumor therapy, surgery), psychological support, the involvement of algologists (intervention methods of therapy), intensified research on the prevention and treatment of pain syndromes, as well as standardization of chronic assessment of pain.