Chronic pain after COVID-19: implications for rehabilitation

Kemp, Harriet; Corner, Evelyn J; Colvin, Lesley

doi:10.1016/j.bja.2020.05.021

Cited by 158 publications

(184 citation statements)

References 40 publications

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“…Those who survive are at high risk of sarcopenia, malnutrition, depression, and delirium 2. Post-covid-19 chronic pain may affect patients of any age but seems to be commoner in elderly patients 63. Physical symptoms add to the psychosocial impact of disrupted access to health care (such as arrangements for obtaining regular medication), core personal routines (such as walking to local shops), social interactions (such as meeting friends), and lay and professional support networks 64.…”

Section: Supporting Recovery From Covid-19mentioning

confidence: 99%

Management of post-acute covid-19 in primary care

Greenhalgh

Knight

A’Court

et al. 2020

BMJ

1,375

1,360

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Section: Supporting Recovery From Covid-19mentioning

confidence: 99%

Management of post-acute covid-19 in primary care

Greenhalgh

Knight

A’Court

et al. 2020

BMJ

1,375

1,360

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“…Patients who survive a critical illness often experience disturbances in many aspects, being pain one of the most important topics, but unfortunately on many occasions during the stay in the units adequate care is not taken to improve it. (2) This study would quantify the impairment on quality life after ICU admission, as well as the incidence of chronic pain, anxiety, depression and PTSD. The health status derived from our analysis could be used in economic evaluations of healthcare systems and long-term impact and consequences of the pandemic.…”

Section: Discussionmentioning

confidence: 99%

“…(3)(4) (5) Critical care survival has been reported as 16-37%, and this will result in an unimaginable size of a cohort of critical care survivors given the number of global infections. (2) Critical care patients can present a signi cant worsening of their health status and deterioration in the quality of life. In 2012 the Society of Critical Care de ned a new term, the Post-intensive Care Syndrome (PICS) de ned the syndrome as the appearance or worsening of the physical, mental or cognitive state after a critical illness that was maintained beyond hospitalization.…”

Section: Introductionmentioning

confidence: 99%

Rationale and Study Design of an Early Care, Therapeutic Education, and Psychological Intervention for the Management of Post-intensive Care Syndrome and Chronic Pain After Coronavirus Disease 2019 (PAIN-COVID): Study protocol for a randomized controlled trial

Ojeda

Calvo

Cuñat

et al. 2020

Preprint

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Background: Critically ill patients with COVID-19 disease are an especially susceptible population to develop Post-intensive Care Syndrome (PICS) due to acute respiratory distress syndrome (ARDS). Patients can suffer acute severe pain and may have long-term deterioration in mental, cognitive, and functional health after discharge. However, few controlled trials are evaluating interventions for the prevention and treatment of PICS. The study hypothesis is that a specific care program based on early therapeutic education and a psychological intervention improves the quality of life of patients at risk of developing PICS and chronic pain after COVID-19 disease. The primary objective is to determine if the program is superior to standard-of-care on health-related life quality at six months after hospital discharge. The secondary objectives are to determine if the intervention is superior to standard care, evaluating the health-related life quality, the incidence of chronic pain and the degree of functional limitation, the incidence of anxiety, depression, and post-traumatic stress syndrome at 3 and 6 months after hospital discharge.Methods: The PAINCOVID trial is a unicentric randomized, controlled, patient blinded superiority trial with two parallel groups. The primary endpoint is the health-related quality of life at six months after hospital discharge, and randomization will be performed with a 1:1 allocation. This paper details the methodology and statistical analysis plan of the trial and was submitted before outcome data were available.Discussion: This the first randomized clinical trial assessing the effectiveness of an early care therapeutic education, and psychological intervention for the management of PICS and Chronic Pain after COVID-19. The intervention will serve as a sample of the need to implement early care programs on early stages, having an incalculable impact given the current scenario of the pandemic.Trial registration: This study is being in accordance with the tenets of the Helsinki Declaration, and has been approved by the authors’ institutional review board Comité Ético de Investigación Clínica del Hospital Clinic de Barcelona (approval number: HCB/2020/0549) and was registered on May 9, 2020 at clinicaltrials.gov (NCT04394169).

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“…Reports of neurological sequelae after COVID-19 infection is increasing by the time associated with the involvement of ACE2 receptor in the neural tissue. Based on these reports, COVID-19 infection could manifest as painful symptoms that require pain medications [ 24 , 25 ].…”

Section: Classification Of Viral Infection Differentiated By Its Causmentioning

confidence: 99%

“…The management of this manifestations is similar with another viral infection: symptomatic therapy depends on the symptoms occurred in patients. Further research is needed to understand how the SARS-CoV-2 could damage and impact musculoskeletal systems [ 24 , 25 ]. There is no specific treatment to treat COVID-19 as the researches for this infection is still on going.…”

Section: Classification Of Viral Infection Differentiated By Its Causmentioning

confidence: 99%

Pain related viral infections: a literature review

Widyadharma

Dewi

Wijayanti

et al. 2020

Egypt J Neurol Psychiatry Neurosurg

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Pain is a common health problem all around the world. The pain symptoms are various depending on the underlying disease or the direct cause of pain itself. Viral infection could cause arthralgia or acute-onset arthritis, moreover in pandemic era of SARS-CoV-2 infection. The patients might experience arthritis, arthralgia, joint pain, or musculoskeletal pain. Viral infection including parvovirus B19, hepatitis virus, human immunodeficiency virus, arthropod-borne virus, and coronavirus could cause various types of pain. The pathogenesis of these symptoms is similar to each other despite of different causative organism. This review will discuss about pain caused by various causative organisms.

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Chronic pain after COVID-19: implications for rehabilitation

Cited by 158 publications

References 40 publications

Management of post-acute covid-19 in primary care

Management of post-acute covid-19 in primary care

Rationale and Study Design of an Early Care, Therapeutic Education, and Psychological Intervention for the Management of Post-intensive Care Syndrome and Chronic Pain After Coronavirus Disease 2019 (PAIN-COVID): Study protocol for a randomized controlled trial

Pain related viral infections: a literature review

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