Chronic Osteomyelitis Caused by Haemophilus parainfluenzae

Abstract

This case report illustrates the complex management of chronic osteomyelitis in pediatric patients, its sequelae, and the importance of considering treatment of atypical pathogens.

Nanopore Sequencing Using the Full-Length 16S rRNA Gene for Detection of Blood-Borne Bacteria in Dogs Reveals a Novel Species of Hemotropic Mycoplasma

“…In addition, a diverse range of putative pathogenic bacteria that show evidence in the literature of being opportunistic pathogens with disease-causing potential in humans were also detected by our method at read counts above the contaminant read threshold ( Table 4 ). Environmental bacteria that can opportunistically cause infections in humans, such as Brucella intermedia ( 57 – 59 ), Burkholderia gladioli ( 60 – 63 ), Haemophilus parainfluenzae ( 64 – 68 ), Paracoccus yeei, and Psychrobacter meningitidis ( 69 – 71 ), were detected from our Cambodian dog blood samples. Moreover, bacterial species that may be associated with the canine oral microbiome, and etiological agents responsible for canine bite wound infections, were also identified, including Pasteurella canis ( 72 – 74 ) and Neisseria animaloris ( 75 , 76 ).…”

Septic Arthritis Caused by Haemophilus parainfluenzae: A Pediatric Case Report and Literature Review

“…2 Reports of septic arthritis (SA) and osteomyelitis caused by H. parainfluenzae in children are extremely rare, and information on its clinical characteristics and outcomes has been quite limited. [3][4][5] To our knowledge, this may be the first pediatric case report of SA of the hip caused by H. parainfluenzae. We also conducted a literature review on the risk factors and management of osteoarticular infection caused by H. parainfluenzae.…”

“…We summarized previously reported cases of SA and osteomyelitis caused by H. parainfluenzae in children and adults in Table 2. 3–23 A literature search in PubMed was conducted using the following search terms: “ Haemophilus parainfluenzae ” and “arthritis” or “osteomyelitis.” English articles, published before April 1, 2022, were included regardless of patient age. The literature review included 21 cases, ranging in age from 8 months to 95 years.…”

“…2 Reports of septic arthritis (SA) and osteomyelitis caused by H. parainfluenzae in children are extremely rare, and information on its clinical characteristics and outcomes has been quite limited. 3–5…”

Pediatric Long Bone Fractures After Dog Bites: A Case Series and Systematic Review

“…Data regarding long-term sequelae of dog bite fractures in long bones is currently scarce. A case report by Ramachandran et al discussed a pediatric patient with a pathologic fracture of the tibia, due to underlying osteomyelitis, with a remote history of a dog bite in the same region [29]. This emphasizes the fact that any dog bite-related long bone fracture can lead to a deeper infection with associated morbidity.…”