Chronic Obstructive Pulmonary Disease Is Associated With Short-Term Complications Following Total Knee Arthroplasty

Yakubek, George; Curtis, Gannon L.; Khlopas, Anton; Faour, Mhamad; Klika, Alison K.; Mont, Michael A.; Barsoum, Wael K.

doi:10.1016/j.arth.2018.03.011

Cited by 39 publications

(30 citation statements)

References 19 publications

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“…The majority of these risk factors were associated with perioperative morbidity or mortality in previous studies on pancreatic resection results . Overall morbidity after a pancreaticoduodenectomy associated with 90‐day mortality included preoperative factors that are considered risk factors for superficial and deep surgical site infection, pneumonia, unplanned intubation, renal insufficiency, and urinary tract infections . COPD is a crucial patient‐related risk factor for postoperative pulmonary complications .…”

Section: Discussionmentioning

confidence: 98%

“…Overall morbidity after a pancreaticoduodenectomy associated with 90‐day mortality included preoperative factors that are considered risk factors for superficial and deep surgical site infection, pneumonia, unplanned intubation, renal insufficiency, and urinary tract infections . COPD is a crucial patient‐related risk factor for postoperative pulmonary complications . Preoperative CKD is associated with an increased risk of complications and respiratory failure after pancreatic resection .…”

Section: Discussionmentioning

confidence: 99%

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Age comorbidity scores as risk factors for 90‐day mortality in patients with a pancreatic head adenocarcinoma receiving a pancreaticoduodenectomy: A National Population‐Based Study

et al. 2019

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Background:To estimate easily assessed preoperative factors for predicting 90day mortality in patients with a pancreatic head adenocarcinoma (PHA) receiving a pancreaticoduodenectomy. Methods: We analyzed data from the Taiwan Cancer Registry Database of patients with a PHA who received a pancreaticoduodenectomy. Basic demographic characteristics, including gender and age, were categorized. The selection of preoperative comorbidities was based on the preoperative American Society of Anesthesiologists score and Charlson comorbidity index. Results: We enrolled 8490 patients with a PHA who received a pancreaticoduodenectomy without distant metastasis. Currently, a pancreaticoduodenectomy for a PHA achieves an overall 90-day mortality rate of 8.39%. Univariate and multivariate Cox regression analyses indicated that an older age (65-74 and ≥75 years) and specific comorbidities (chronic obstructive pulmonary disease, chronic kidney disease, dementia, and sepsis) were significant independent prognostic factors for predicting 90-day mortality after a pancreaticoduodenectomy. After adjustment, the adjusted 572 |

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Age comorbidity scores as risk factors for 90‐day mortality in patients with a pancreatic head adenocarcinoma receiving a pancreaticoduodenectomy: A National Population‐Based Study

et al. 2019

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“…Extended LOS was determined to be an inpatient hospital stay >7 days (LOS), based on previous literature. 11 Postoperative complications were classified into clinically relevant groups according to the type of complication. These groups include wound (superficial surgical site wound infection, deep wound infection, organ or space infections, and wound dehiscence), pulmonary (pneumonia, reintubation, and failure to wean off ventilator for greater than 48 hours), cardiac (cardiac arrest and myocardial infarction), renal (renal insufficiency and renal failure), thromboembolic (pulmonary embolism, deep vein thrombosis, and stroke), and sepsis (sepsis and septic shock).…”

Section: Methodsmentioning

confidence: 99%

Impact of Chronic Obstructive Pulmonary Disease on Postoperative Complications Following Simultaneous Bilateral Total Knee Arthroplasty

Mancino

et al. 2019

J Knee Surg

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For patients who qualify, simultaneous bilateral total knee arthroplasty (TKA) is a viable option for the treatment of bilateral symptoms. However, the incidence of chronic obstructive pulmonary disease (COPD) has been steadily rising over the past few decades and may impact those who qualify as candidates for bilateral TKA. As such, the aim of this study was to determine the impact of COPD on postoperative outcomes in patients who receive simultaneous bilateral TKA. A retrospective cohort study was conducted utilizing data provided through the American College of Surgeons National Surgical Quality Improvement Program. All patients who had undergone simultaneous bilateral TKA between 2007 and 2016 were identified and further stratified into groups based upon the COPD status. Incidence of adverse events after TKA in the acute postoperative period was evaluated with univariate and multivariate analyses. COPD was found to be an independent risk factor for the development of major (odds ratio [OR]: 2.5; p = 0.015), renal (OR: 5.1; p = 0.02), and thromboembolic complications (OR: 2.5; p = 0.027). In addition, patients with COPD were at increased risk for having an extended hospital length of stay (LOS; p < 0.001) and development of urinary tract infections (p < 0.001). Patients with COPD are at higher risk for development of overall major complications, as well as renal and thromboembolic complications after simultaneous bilateral TKA. Interestingly, patients were not at increased risk for the development of pulmonary or wound complications. When considering a staged versus simultaneous bilateral TKA, surgeons should be aware of the impact COPD status has on the postoperative complication rate.

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“…This study found an association of COPD with poor functional outcome in patients with aSAH. While such an association has not been previously assessed in patients with aSAH, a study found that COPD increased the incidence of discharge to nursing homes and rehabilitation facilities after surgery [20], and another study found that the discharge destination is a surrogate for mRS functional outcome in stroke survivors [21]. More research is needed to con rm the association of COPD with poor functional outcome in patients with aSAH.…”

Section: Functional Outcomementioning

confidence: 99%

“…[25] Yakubek et al published a study found that in patients undergoing total hip arthroplasty, patients with COPD are more likely to experience pneumonia and deep surgical site infection. [20] Two large randomized clinical trials conducted in patients hospitalized for stroke found that prophylactic antibiotics did not reduce the incidence of pneumonia. [9,10] A possible explanation for the lack of bene t is that the included patients have a general risk for pneumonia but not high risk, with 7-16% patients developing pneumonia in the control group.…”

Section: Infection Complicationsmentioning

confidence: 99%

Impact of Chronic Obstructive Pulmonary Disease on In-hospital Mortality in Patients with Aneurysmal Subarachnoid Hemorrhage: An Observational Cohort Study with Propensity Score Matching

Yao

Wang

et al. 2020

Preprint

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Objective: Chronic obstructive pulmonary disease (COPD) has been associated with several complications and mortality in acutely ill patients. For patients with aneurysmal subarachnoid hemorrhage (aSAH), the association between COPD and clinical outcomes remains unclear. Methods: In this retrospective cohort study, we analyzed consecutive aSAH patients admitted to the West China Hospital between 2009 and 2019. Propensity score matching was performed to obtain the adjusted odds ratios (ORs) with 95% CI. The primary outcome was in hospital mortality.Results: Using a ten-year clinical database from a large university medical center, 5643 patients with aSAH were identified, of whom 377 (7.9%) also had COPD. After matching, 289 patients were included in COPD group and 1156 in non-COPD groups. COPD was associated with increased in-hospital mortality (OR 1.63, 95% CI 1.02-2.62) and poor functional outcome at discharge (OR 1.37, 95% CI 1.04-1.80). Similarly, patients with COPD had significantly longer length of hospital stay, higher odds of seizure (OR 2.05, 95% CI 1.04-4.04), pneumonia (OR 3.10, 95% CI 2.38-4.04), intracranial infection (OR 1.62, 95% CI 1.14-2.29), urinary tract infection (OR 1.59, 95% CI 1.16-2.20) and bloodstream infection(OR 3.27, 95% CI 1.74-6.15). Conclusions: Among aSAH patients, COPD is associated with increased mortality. COPD represents a significant risk factor for pneumonia and seizure.

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Chronic Obstructive Pulmonary Disease Is Associated With Short-Term Complications Following Total Knee Arthroplasty

Cited by 39 publications

References 19 publications

Age comorbidity scores as risk factors for 90‐day mortality in patients with a pancreatic head adenocarcinoma receiving a pancreaticoduodenectomy: A National Population‐Based Study

Age comorbidity scores as risk factors for 90‐day mortality in patients with a pancreatic head adenocarcinoma receiving a pancreaticoduodenectomy: A National Population‐Based Study

Impact of Chronic Obstructive Pulmonary Disease on Postoperative Complications Following Simultaneous Bilateral Total Knee Arthroplasty

Impact of Chronic Obstructive Pulmonary Disease on In-hospital Mortality in Patients with Aneurysmal Subarachnoid Hemorrhage: An Observational Cohort Study with Propensity Score Matching

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