Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the Commonwealth of Independent States: rationale and design of the CORE study

Abstract

BackgroundMain treatable Chronic Respiratory Diseases (CRDs) like Chronic Obstructive Pulmonary Disease (COPD), Bronchial Asthma (BA) and Allergic Rhinitis (AR) are underdiagnosed and undertreated worldwide. CORE study was aimed to assess the point prevalence of COPD, BA and AR in the adult population of major cities of Commonwealth of Independent States (CIS) countries – Azerbaijan, Kazakhstan, and Ukraine based on study questionnaires and/or spirometry, and to document risk factors, characterize the COPD, BA and AR population to provide a clearer “epidemiological data”.MethodsA descriptive, cross-sectional, population-based epidemiological study conducted from 2013 to 2015 with two-stage cluster geographical randomization. Interviewers conducted face-to-face visits at respondent’s household after informed consent and eligibility assessment including interviews, anthropometry, spirometry (with bronchodilator test) and completion of disease-specific questionnaires.ResultsTwo thousand eight hundred forty-two respondents (Ukraine: 964 from Ukraine; 945 from Kazakhstan; 933 Azerbaijan) were enrolled. Mean age was 40–42 years and males were 37%–42% across three countries. In Kazakhstan 62.8% were Asians, but in Ukraine and in Azerbaijan 99.7% and 100.0%, respectively, were Caucasians. Manual labourers constituted 40.5% in Ukraine, 22.8% in Kazakhstan and 22.0% in Azerbaijan, while office workers were 16.1%, 31.6% and 36.8% respectively. 51.3% respondents in Ukraine, 64.9% in Kazakhstan and 69.7% in Azerbaijan were married.ConclusionCORE study collected information that can be supportive for health policy decision makers in allocating healthcare resources in order to improve diagnosis and management of CRDs. The detailed findings will be described in future publications.Trial registrationStudy Protocol Summary is disclosed at GlaxoSmithKline Clinical Study Register on Jun 06, 2013, study ID 116757.Electronic supplementary materialThe online version of this article (10.1186/s12890-017-0471-x) contains supplementary material, which is available to authorized users.

The prevalence, burden and risk factors associated with chronic obstructive pulmonary disease in Commonwealth of Independent States (Ukraine, Kazakhstan and Azerbaijan): results of the CORE study

“…The aim of the study was to evaluate the country-specific point prevalence of COPD, bronchial asthma and allergic rhinitis in selected CIS countries in order to obtain a clear “epidemiological picture” of the disease. The rationale and design of the CORE study (including the key steps of the recruitment phase, inclusion and exclusion criteria, study population, demographic characteristics, employment status, education and marital status of participants and the questionnaires used in the study) have been described previously [ 9 ]. In this manuscript, data obtained on the prevalence and burden of COPD will be presented.…”

Ontology-Based Model to Support Ubiquitous Healthcare Systems for COPD Patients

“…Recently, there has been growing interest in COPD. Most studies focus on the causes [9], symptoms [10], diagnosis [11], prevention [12], treatment [13], the number of patients [14], and economic costs [15]. On the other hand, few statistical studies examine the progression of the disease with and without quitting smoking [16].…”

“…ix. History: History can be considered as a risk factor of subsequent COPD exacerbations, where clinical studies [11,33] confirm that patients with previous exacerbation history are more susceptible than others.…”

Correction to: Chronic obstructive pulmonary disease, bronchial asthma and allergic rhinitis in the adult population within the commonwealth of independent states: rationale and design of the CORE study

“…After publication of this work [ 1 ] it was noticed three author names were spelt incorrectly. Liudmila Iashyna should be Liudmyla Iashyna, Marina Polyanskaya should be Maryna Polianska and Elcan Mamamdbayov should be Eljan Mammadbayov.…”