Chronic Obstructive Pulmonary Disease as a Predictor of Mortality in Patients Undergoing Percutaneous Coronary Intervention

Selvaraj, C; Gurm, Hitinder S.; Gupta, Ritesh; Ellis, Stephen G.; Bhatt, Deepak L.

doi:10.1016/j.amjcard.2005.05.016

Cited by 63 publications

(53 citation statements)

References 9 publications

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“…27,28,[30][31][32][33][34] Behar et al, 33 using data from the Secondary Prevention Reinfarction Israel Nifedipine Trial (SPRINT) study, which was conducted between 1981 and 1983, reported a 7% prevalence of COPD among 5839 survivors of MI. The age group of the SPRINT study was comparable to that of the current study, and the investigators reported increased incidence of prior history of angina and smoking.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Prognosis of Chronic Obstructive Pulmonary Disease Among 8167 Middle Eastern Patients With Acute Coronary Syndrome

Hadi

Zubaid²,

Mahmeed

et al. 2010

Clinical Cardiology

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Background: The purpose of this study was to report the prevalence and the significance of clinically recognized chronic obstructive pulmonary disease (COPD) during acute coronary syndrome (ACS). Hypothesis: COPD in patients with ACS is associated with worse outcome. Methods: Data were derived from a prospective, multicenter, multinationalstudy of 8167 consecutive patients hospitalized with ACS from February to June 2007 in 6 Middle Eastern countries. Data were analyzed according to the presence or absence of COPD. Demographic, management, and in-hospital outcomes were compared. Results: The prevalence of COPD was 5.3%. When compared with non-COPD patients, COPD patients were older and more likely to have diabetes, hypertension, and dyslipidemia. Atypical presentations were more common in COPD patients (P = 0.001). COPD patients were less likely to be treated with thrombolytic therapy (P = 0.001), β-blockers (P = 0.001), and glycoprotein IIb/IIIa inhibitors, and more likely to receive angiotensin-converting enzyme (ACE) inhibitors. Although there was no difference in in-hospital mortality between the 2 groups, patients with COPD were more likely to have heart failure (P = 0.001). Despite the fact that COPD patients with ST-segment elevation myocardial infarction were less likely to receive thrombolytic therapy, they suffered more bleeding complications (2.8% vs 1%, P = 0.04), resulting in prolonged hospitalization. COPD was not an independent predictor of increased in-hospital mortality. Conclusions: In this large cohort of patients with ACS, the prevalence of COPD was 5·3%. Atypical presentation is common among COPD patients, and this may result in delayed therapy. ACS in COPD patients was associated with higher risk of heart failure and major bleeding complications without increased risk of in-hospital mortality.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Prognosis of Chronic Obstructive Pulmonary Disease Among 8167 Middle Eastern Patients With Acute Coronary Syndrome

Hadi

Zubaid²,

Mahmeed

et al. 2010

Clinical Cardiology

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“…There did not seem to be any literature examining the medical treatment of patients with COPD and ASCVD. But recently, an article published by Selvaraj et al 19 reported that COPD was a predictor of mortality in patients undergoing percutaneous coronary intervention. Their study showed a similar survival at 5 years.…”

Section: Comparison With Previous Studiesmentioning

confidence: 99%

Long-Term Survival of Patients With Chronic Obstructive Pulmonary Disease Undergoing Coronary Artery Bypass Surgery

et al. 2006

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Background— Chronic obstructive pulmonary disease (COPD) is associated with increased in-hospital mortality in patients undergoing coronary artery bypass surgery (CABG). Long-term survival is less well understood. The present study examined the effect of COPD on survival after CABG. Methods and Results— We conducted a prospective study of 33 137 consecutive isolated CABG patients between 1992 and 2001 in northern New England. Records were linked to the National Death Index for long-term mortality data. Cox proportional hazards regression was used to calculate hazard ratios (HRs). Patients were stratified by: no comorbidities (none), COPD, COPD plus comorbidities, and other comorbidities with no COPD. There were 131 434 person years of follow-up and 5344 deaths. The overall incidence rate (deaths per 100 person years) was 4.1. By group, rates were: 2.1 (none), 4.0 (COPD alone), 5.5 (other), and 9.4 (COPD plus; log rank P <0.001). After adjustment, survival with COPD alone was worse compared with none (HR, 1.8; 95% CI, 1.6 to 2.1; P <0.001). Patients with other comorbidities compared with none had even worse survival (HR, 2.2; 95% CI, 2.1 to 2.4; P <0.001). Patients with COPD plus other comorbidities compared with none had the worst long-term survival (HR, 3.6; 95% CI, 3.3 to 3.9; P <0.001). Conclusions— Patients with only COPD had significantly reduced long-term survival compared with patient with no comorbidities. Patients with COPD and ≥1 other comorbidity had the worst survival rate when compared with all of the other groups.

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“…На сегодняшний день имеются лишь отдельные сообщения о результатах ЧКВ у пациентов с сопут-ствующей ХОБЛ, имеющие достаточно противоречи-вый характер [8,9]. Так, в исследовании Selvaraj C. отмечено отрицательное влияние ХОБЛ на резуль-таты реваскуляризации по поводу ИМ и увеличение риска смертности в отдаленном периоде в 2 раза [8].…”

Section: Discussionunclassified

“…Так, в исследовании Selvaraj C. отмечено отрицательное влияние ХОБЛ на резуль-таты реваскуляризации по поводу ИМ и увеличение риска смертности в отдаленном периоде в 2 раза [8]. Nishiyamа К. показал, что ХОБЛ приводила к значи-мому повышению корригированного риска общей смертности после ЧКВ, причем ее роль как предик-тора плохих результатов реваскуляризации в отдален-ном периоде не была связана с технологией реперфу-зий [9].…”

Section: Discussionunclassified

“…АкШ, n (%) 2 (11,8) 25 (14,9) 0,7306 поражения коронарного русла. В ряде исследований показано, что при ХОБЛ стенозы располагаются в более дистальных участках коронарных артерий и имеют большую протяженность [16].…”

Section: Discussionunclassified

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Outcomes of Percutaneous Coronary Intervention in St Elevation Myocardial Infarction and Chronic Obstructive Pulmonary Disease

et al. 2017

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Chronic Obstructive Pulmonary Disease as a Predictor of Mortality in Patients Undergoing Percutaneous Coronary Intervention

Cited by 63 publications

References 9 publications

Prevalence and Prognosis of Chronic Obstructive Pulmonary Disease Among 8167 Middle Eastern Patients With Acute Coronary Syndrome

Prevalence and Prognosis of Chronic Obstructive Pulmonary Disease Among 8167 Middle Eastern Patients With Acute Coronary Syndrome

Long-Term Survival of Patients With Chronic Obstructive Pulmonary Disease Undergoing Coronary Artery Bypass Surgery

Outcomes of Percutaneous Coronary Intervention in St Elevation Myocardial Infarction and Chronic Obstructive Pulmonary Disease

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