Chronic Obstructive Pulmonary Disease and Anxiety and Depression Disorders: Prospective Cohort Study in Primary Care

Mc, Josep; Pere, G; Mj, Ramon; Ferran, B; Josep, P; Marta, Ollyvia Freeska Dwi; Miquel, Anne

doi:10.21767/2577-0578.10027

Cited by 1 publication

(1 citation statement)

References 28 publications

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“…Andrenas et al ascertained that most of the patients evaluated their stressful situation as a threat, and challenging issue which inversely affects their coping skills with distressful disorders [21]. They also believed that such worrying conditions have a harmful effect on patients' mental health and their quality of life [22][23][24]. Literature also revealed that deterioration in the immune system of patients with anxiety and depression is more likely which eventually weakens their resistance toward pathogens [25][26][27].…”

Section: Discussionmentioning

confidence: 99%

Exposure to Stressful Life Events among Patients with Chronic Obstructive Pulmonary Disease: A Prospective Study

Zohal

Rafiei

Rastgoo

et al. 2020

Advances in Respiratory Medicine

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Introduction: Although depression and anxiety have been widely investigated among patients with chronic obstructive pulmonary disease (COPD), experiencing stressful life events and its effect on increasing risk of exacerbations was rarely assessed. This study aimed to clarify the association between facing with stressful events among COPD patients and their disease severity leading to hospitalization. Material and methods: A prospective study was conducted among 128 COPD patients from the population of Qazvin, a north-west, industrialized city of Iran from December 2017 to December 2018. Patients were followed up for one-year and their related measures were gathered. To compare variables among patients stratified by reporting stressful life conditions, Pearson’s chi-square and Fisher’s exact tests were used. Furthermore, to assess the effect of several covariates on the response variable, a logistic regression modelling was applied. Results were reported in form of odds ratios and their 95% confidence intervals. Results: Study findings affirmed that patients who had experienced stressful situation had lower BMI, were retired, experienced more frequent exacerbations, and reported higher levels of anxiety/ depression. Moreover, those with stressful conditions were among current or former smokers (p < 0.05). Logistic regression analysis revealed that facing with stressful situations was significantly associated with the severity of COPD disease (OR 1.9; 95% CI 2.5 to 5.6), smoking habit (OR 2.8; 95% CI 1.6 to 4.2; OR 1.5; 95% CI 1.4 to 2.2), and hospitalization during one-year follow up (OR 1.2; 95% CI 1 to 3.3). Conclusions: To improve health outcomes of COPD patients, close attention should be given to their psychological disorder and appropriate strategies should be applied to reduce patients’ exposure to stressful life events and subsequent anxieties.

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