Chronic obstructive pulmonary disease - diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based on clinical phenotypes. Position paper of the Czech Pneumological and Phthisiological Society

The Relation Between Clinical Phenotypes, GOLD Groups/Stages and Mortality in COPD Patients – A Prospective Multicenter Study

“…In the past decade, a concept of COPD phenotyping and treatable traits has emerged, reflecting specific clinical, pulmonary and extrapulmonary features of the each particular case. [2][3][4][5][6] The main advantage of this concept is that COPD patients may receive a more personalized type of treatment. 2,7 The most widely used phenotyping scheme was introduced in Spain eight years ago.…”

“…Six clinical phenotypes of COPD have been defined, including emphysematous, bronchitic, asthma/COPD overlap (ACO), pulmonary cachexia, frequent exacerbator and bronchiectases with COPD overlap (BCO). 6 Each of these clinical phenotypes has specific clinical, radiological, laboratory or functional appearance. 6 At the same time, in our concept, each of these phenotypes is considered an independent treatable trait.…”

“…6 Each of these clinical phenotypes has specific clinical, radiological, laboratory or functional appearance. 6 At the same time, in our concept, each of these phenotypes is considered an independent treatable trait. 6 The treatment strategy presented in the recent position paper of the Czech Pneumological and Phthisiological Society on COPD management is divided into five strata: risk elimination, basic treatment, phenotype-specific treatment, treatment of respiratory failure and palliative care, and treatment of comorbidities.…”

“…6 The treatment strategy presented in the recent position paper of the Czech Pneumological and Phthisiological Society on COPD management is divided into five strata: risk elimination, basic treatment, phenotype-specific treatment, treatment of respiratory failure and palliative care, and treatment of comorbidities. 6 When compared to the Spanish COPD management guidelines, an important difference is that we recognize the possibility of multiple clinical phenotypes' coexistence in a single COPD individual (one patient = one or more phenotypes). 6 This concept facilitates optimization of treatment strategy in relation to specific disease patterns of each COPD individual.…”

“…6 When compared to the Spanish COPD management guidelines, an important difference is that we recognize the possibility of multiple clinical phenotypes' coexistence in a single COPD individual (one patient = one or more phenotypes). 6 This concept facilitates optimization of treatment strategy in relation to specific disease patterns of each COPD individual. 6,[9][10][11] Apart from treatment guidance, phenotypes may also have certain prognostic properties.…”