“…CML is characterized by the genetic translocation, t (9; 22) (q34; q11.2), that results in the fusion of Abelson gene (ABL1) from chromosome 9q34 with the breakpoint cluster region (BCR) gene on chromosome 22q11.2 [5,6] . The Philadelphia chromosome translocation is observed in 90% to 95% of CML patients whereas more, complex translocations, involving a third chromosome are present in only 5% to 8% of the patients [7,8] . Although variant translocations might involve any chromosome, the distribution of the breakpoints is nonrandom and, usually seen at some specific chromosomal bands, including 1p36, 2p22,3p21, 4q25,5q31, 6p21, 9q22, 10q22, 11q13, 12p13, 16p13,17p13,17q21, 17q25, 19q13, 21q22, 22q12, and 22q13 [9–16] .…”