Chronic meningococcaemia: a forgotten meningococcal disease

Association of chronic meningococcemia with infection by meningococci with underacylated lipopolysaccharide

“…7 The clinical characteristics of included patients with chronic meningococcemia were similar to previous reports. 4,10,11 We found that chronic meningococcemia can occur at any age and is characterized by a long initial phase of general malaise, recurrent fever and weight loss, followed by arthralgia and rash. The benign character of the disease was confirmed as only one patient had residual symptoms.…”

Value of a Novel Neisseria Meningitidis–Specific Polymerase Chain Reaction Assay in Skin Biopsy Specimens as a Diagnostic Tool in Chronic Meningococcemia

“…5 The cutaneous manifestations, which are observed in up to 50% of the cases, are variable, including purpuric papules and nodules, and urticarial eruptions. 6,7 Therefore, the clinical presentations of our 2 patients were suggestive of CM. Nevertheless, in the patient presenting with a 10-day course, the disease could also be defined as occult meningococcemia.…”

Chronic Meningococcemia

“…Alongside the classic acute forms of the disease, there are rare chronic (benign) forms, defined as a meningococcal sepsis of at least one week duration without meningeal symptoms and characterized by a prolonged clinical course with intermittent fever, rash and migratory arthralgia in healthy individuals [7]. Chronic meningococcemia may be self-limiting, but meningitis and death can occur as a late complication [8].…”