2008
DOI: 10.1590/s1413-86702008000600026
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Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia

Abstract: Meningitis is a common evolution in progressive disseminated histoplasmosis in children, and is asymptomatic in many cases. In leukemia, the impaired of the T cells function can predispose to the disseminated form. The attributed mortality rate in this case is 20%-40% and the relapse rate is as high as 50%; therefore, prolonged treatment may be emphasized. We have described a child with acute myeloid leukemia (AML), that developed skin lesions and asymptomatic chronic meningitis, with a good evolution after pr… Show more

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Cited by 6 publications
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“…We found 1159 studies and included 108 manuscripts published between 1962 and 2022, totaling 298 patients 7–10,12–115 . We excluded 38 articles that could not be retrieved.…”
Section: Resultsmentioning
confidence: 99%
“…We found 1159 studies and included 108 manuscripts published between 1962 and 2022, totaling 298 patients 7–10,12–115 . We excluded 38 articles that could not be retrieved.…”
Section: Resultsmentioning
confidence: 99%
“…Histoplasmosis is a rare fungal infection observed in the bone marrow, and compromised immunity due to malignancies, chemotherapy, organ transplantation, and AIDS are considered important predisposing factors for disseminated histoplasmosis [5, 6]. Pancytopenia may be associated with histoplasmosis, particularly in patients showing hemophagocytosis [7, 8].…”
Section: Discussionmentioning
confidence: 99%