Chronic medical conditions mediate the association between depression and cardiovascular disease mortality

Atlantis, Evan; Shi, Zumin; Penninx, Brenda; Wittert, Gary; Taylor, Anne; Almeida, Osvaldo P.

doi:10.1007/s00127-011-0365-9

Cited by 45 publications

(27 citation statements)

References 50 publications

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“…Chronic disease was related to depression in our study, which is similar to what has been reported in the literature (8,(16)(17)(18). Insufficient daily activities were related to depression too, and those who were satisfied with daily activities had less depression (19).…”

Section: Discussionsupporting

confidence: 90%

Depression Prevalence and Underlying Risk Factors in the Elderly of Hamadan, Iran

Rabiei

Ghaleiha

Hosseini

et al. 2015

Avicenna J Neuro Psych Physio

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Background: Depression is the most frequent psychiatric disorder in the elderly. Nowadays, because of the rise in the absolute number and proportion of elders in societies, the numbers of elders with this condition may be increasing. Objectives: This study was conducted to evaluate depression prevalence and its underlying risk factors in the elder population of Hamadan, Iran. Patients and Methods:In a descriptive-analytic cross-sectional study, 240 over 65 year old subjects (121 males, 119 females), were enrolled in the study. Depression was diagnosed based on the Center of Epidemiological Studies Depression Scale Revised (CESD-R) questionnaire and pooled data were analyzed by SPSS 16 software (SPSS Inc. Chicago IL., USA). Results: Of the total number of 240 elderly, 116 (48.3%) had depression (score 17 or more, based on CESD-R questionnaire). Women were significantly more affected (61.3% vs. 35.7%, P value < 0.001). Other factors, which revealed a significant relationship with depression, were: illiteracy, being jobless or retired, having a chronic disease and dissatisfaction of daily activities. After performing a logistic regression method, only two variables (sex and dissatisfaction of daily activities) were significantly related to depression in the study population. Conclusions: In our study, depression had a remarkable prevalence in elderly, especially in women and in those who suffered from inactive or sedentary life.

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Section: Discussionsupporting

confidence: 90%

Depression Prevalence and Underlying Risk Factors in the Elderly of Hamadan, Iran

Rabiei

Ghaleiha

Hosseini

et al. 2015

Avicenna J Neuro Psych Physio

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“…In the overall US adult population, the estimated prevalence of hyperlipidemia based on clinical data is 13.4% (NHANES, 2009-2010). 72 Estimates of the prevalence of hypertension (median: 35.0%; range: 10.0%-68.0%) among persons with SMI were extracted from 29 studies 43,46,47,50,53,56,57,60-68,70,71,73-83 (37 measures). The median prevalence estimates of hypertension among studies using claims (35.3%), clinical (37.8%) and other (e.g.…”

Section: Resultsmentioning

confidence: 99%

Review of the evidence: prevalence of medical conditions in the United States population with serious mental illness

Janssen

McGinty

Azrin

et al. 2015

General Hospital Psychiatry

132

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Objective Persons with serious mental illness (SMI) have high rates of premature mortality from preventable medical conditions, but this group is underrepresented in epidemiologic surveys and we lack national estimates of the prevalence of conditions such as obesity and diabetes in this group. We performed a comprehensive review to synthesize estimates of the prevalence of 15 medical conditions among the population with SMI. Method We reviewed studies published in the peer-reviewed literature from January 2000-August 2012. Studies were included if they assessed prevalence in a sample of 100 or more US adults with schizophrenia or bipolar disorder. Results 57 studies were included in the review. For most medical conditions, the prevalence estimates varied considerably. For example, estimates of obesity prevalence ranged from 26% to 55%. This variation appeared to be due to differences in measurement (e.g. self-report versus clinical measures) and underlying differences in study populations. Few studies assessed prevalence in representative, community samples of persons with SMI. Conclusions In many studies, the prevalence of medical conditions among the population with SMI was higher than among the overall US population. Screening for and monitoring of these conditions should be common practice in clinical settings serving persons with SMI.

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“…3 A wide variety of demographic and lifestyle factors have been associated with depression. [2][3][4][5] Obesity, anxiety, insomnia, cardiovascular disease, diabetes, and lower urinary tract symptoms are conditions associated with an increased risk of depression and these have also been linked to sleep disorders 2,5,6 ; the most common sleep disorder in men is obstructive sleep apnea (OSA).…”

Section: Introductionmentioning

confidence: 99%

Associations of Undiagnosed Obstructive Sleep Apnea and Excessive Daytime Sleepiness With Depression: An Australian Population Study

Lang

Appleton

Vakulin

et al. 2017

Journal of Clinical Sleep Medicine

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Study Objectives: To determine whether undiagnosed obstructive sleep apnea (OSA) and/or excessive daytime sleepiness are associated with symptomatic depression in Australian men. Methods: Participants were randomly selected, urban community dwelling men aged 40 to 88 years without a prior diagnosis of OSA. Clinically significant depressive symptoms were assessed using the Beck Depression Inventory-1A or Centre for Epidemiological Studies Depression Scale (2007)(2008)(2009)(2010). A random sample of men (n = 788) undertook full at-home unattended polysomnography (Embletta X100, Broomfield, Colorado, United States) and completed the Epworth Sleepiness Scale questionnaire (2010)(2011)(2012). Results: Undiagnosed severe obstructive sleep apnea (apnea-hypopnea index ≥ 30 events/h) was associated with depressive symptoms (adjusted odds ratio = 1.98; 95% confidence interval [CI] 1.05-3.73; P = .036). However, a significant interaction was observed between obstructive sleep apnea and excessive daytime sleepiness (P = .03) such that individuals with OSA and excessive daytime sleepiness (Epworth Sleepiness Scale score of 10 or higher) exhibited the strongest associations with depression (mild-moderate apnea: adjusted odd ratio = 3.86; 95% CI 1.87-7.95; severe apnea: adjusted odd ratio = 4.82; 95% CI 1. 42-16.35) when compared to individuals without apnea. Conclusions: Depressive symptoms in men were associated with undiagnosed OSA in the community. It is important that clinicians and primary care practitioners consider screening for depression in men with severe OSA and for OSA in men with depression. Screening for depression should also be considered in men with excessive daytime sleepiness regardless of OSA severity.

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Chronic medical conditions mediate the association between depression and cardiovascular disease mortality

Cited by 45 publications

References 50 publications

Depression Prevalence and Underlying Risk Factors in the Elderly of Hamadan, Iran

Depression Prevalence and Underlying Risk Factors in the Elderly of Hamadan, Iran

Review of the evidence: prevalence of medical conditions in the United States population with serious mental illness

Associations of Undiagnosed Obstructive Sleep Apnea and Excessive Daytime Sleepiness With Depression: An Australian Population Study

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