Chronic Lymphatic Leukemia Associated with Hodgkin’s Disease

Hodgkin’s Disease Variant of Richter’s Syndrome

“…1,4,10,30 An interesting and more etiologically challenging transformation is HD terminally complicating CLL. Although several reports of this were published in the 1940-1970's, 7,13,[17][18][19]27,29,31 some authors refuted the diagnosis as misinterpretation of diffuse histiocytic lymphoma with "Reed-Sternberg-like" cells. 11,20 In recent years, with modern diagnostic tools of immunohistochemistry, flow cytometry and molecular genetics, several further reports of this phenomenon have been confirmed.…”

Gaucher's disease associated with chronic lymphocytic leukaemia, gout and carcinoma

“…Gaucher cells in chronic granulocytic leukaemia were first described by Albrecht (1966) and was suggested to be a phenocopy of Gaucher's disease (Seife et al 1951). Gaucher's disease has been found to have a deficiency of glucocerebrosidase in tissue (Patrick, 1965) and in peripheral white cells .…”

Acute Myelomonocytic Leukemia in a Patient with Hodgkin’s Disease

“…[29] 1970 M 68 acute myelomonocytic + (1) In some patients who died of chronic myelogenous leukemia (CML), Hodgkin's disease was found at post mortem examination [4,5,7], Marked leukocytosis may occur in Hodgkin's disease, and it is possi ble that some of these patients did not have true CML [8,9]. Chronic lymphocytic leukemia (CLL) preceeds Hodgkin's disease more often [6,7,[10][11][12][13][14]. In those instances, it is likely that the patient suffered from two separate neoplastic diseases.…”