Chronic Limb Ischemia due to Thrombosis of an Aneurysmal Degeneration of the Autogenous Vein Graft: A Case Report

Abstract

Nonanastomotic aneurysmal degeneration of a great saphenous vein graft is an unusual condition, despite the common use of this conduit in arterial reconstructions. Vein grafts are at risk of degenerative changes, but the real cause remains unknown. Postoperative graft surveillance with duplex ultrasound scanning is important for maintaining patency of the venous graft. We present a rare case of chronic limb ischemia due to partial thrombosis of an aneurysm of the great saphenous vein graft.

Anti-Inflammatory and Anti-Thrombogenic Properties of Arterial Elastic Laminae

“…Autogenous vein- and arterial graft-based arterial reconstruction is an effective approach for the treatment of occlusive arterial disorders. Autogenous venous and arterial grafts have been considered the most reliable graft types because of their natural properties and performance, although these grafts are prone to thrombosis, inflammation, and intimal hyperplasia, resulting in graft stenosis and failure [ 98 , 99 , 100 , 101 , 102 , 103 ]. However, due to limited quantity, vascular disease, or prior harvests, suitable autogenous grafting materials are often unavailable.…”