Chronic leg ulcers: an underestimated problem in primary health care among elderly patients.

Nelzén, Olle; Bergqvist, David; Lindhagen, A; Hallböök, T

doi:10.1136/jech.45.3.184

Cited by 174 publications

(111 citation statements)

References 3 publications

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“…These results were found to be below the average determined by Nelzen et al 9 (Switzerland), in whose sample 85% were over the age of 64 years with a mean age of 76 years for women and 78 for men. By contrast, the results were similar to Scott et al 10 These difference are justified by different techniques used to collect data, in addition to socioeconomic, cultural and geographic differences characteristic of each sample.…”

Section: Discussioncontrasting

confidence: 42%

Úlcera de perna: um estudo de casos em Juiz de Fora-MG (Brasil) e região

Frade

Cursi

Andrade

et al. 2005

An. Bras. Dermatol.

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BACKGROUND: Leg ulcers are characterized as tissue loss in the lower extremities, generally caused by vascular dysfunction. OBJECTIVES: Verify the clinical and epidemiological profiles of the population sample with leg ulcers treated at the health centers of Juiz de Fora (Brazil). MATERIAL AND METHODS: 124 leg-wound patients were evaluated between January 1999 and August 2001 and submitted to a clinical protocol. RESULTS: The mean age was 64 years, with females in the majority (65.3%). The mean family composition was 3.7 persons, and family income was around US$200.00 (86.8%). Venous insufficiency (90.3%), systemic arterial hypertension (54%), obesity (20.2%) and diabetes mellitus (16.1%) were the most frequent events associated with the ulcers. An association of venous insufficiency and arterial hypertension was frequent in 43.7% of the sample, and significant (p<0.01) to predisposition to the ulcers. These were classified as venous (79%), hypertensive (15.4%), mixed and other (5.6%). The ulcers were generally localized in the distal third of legs (90%) and considered large (>5 cm) in about 90% of the sample, with means of 8.7 cm and 9.6 cm to vertical and horizontal axes, respectively. The ulcers were accompanied mainly by hyperpigmentation (92.7%), lipodermatosclerosis (68.5%) and varicose veins (66.9%), with a mean duration of 94.2 months and 50% of them recurrent. CONCLUSIONS: The data suggested that leg ulcer is an important chronic disease in the elderly and poor population of Juiz de Fora and region. Keywords: Aged; Income; Family income; Leg ulcers/ epidemiology; Varicose veins. Resumo: FUNDAMENTOS: Úlcera de perna (UP) caracteriza-se por perda do tegumento nas extremidades dos membros inferiores causada geral

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Section: Discussioncontrasting

confidence: 42%

Úlcera de perna: um estudo de casos em Juiz de Fora-MG (Brasil) e região

Frade

Cursi

Andrade

et al. 2005

An. Bras. Dermatol.

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“…Chronic wounds were found to predominantly affect elderly patients. Studies in Europe have shown that the prevalence of chronic wounds increases with advancing age from 1.48/1,000 to 36/1,000 population in those over 65 years of age [26][27][28].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and antibiotic susceptibility of bacteria from acute and chronic wounds in Malaysian subjects

Wong

Manikam

Muniandy

2015

J Infect Dev Ctries

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Introduction: Chronic wounds represent a major health burden worldwide. It has been hypothesized that the polymicrobial nature of wounds plays an important role in their healing process. Thus, a review of pathogen frequency and susceptibility patterns in wounds is necessary to provide appropriate guidelines for antimicrobial usage. Methodology: In this study, microbiota and antimicrobial resistance in both acute and chronic wound patients treated at the University of Malaya Medical Centre, Malaysia, were compared. Wound swabs from 84 patients with acute wounds and 84 patients with chronic wounds were collected. The specimens were cultured using standard microbiological techniques. Isolates were then tested for antibiotic sensitivity with the broth microdilution method. Results: Of 210 pathogenic bacteria isolates, Staphylococcus aureus (49; 23.3%) and Pseudomonas aeruginosa (31; 14.8%) were the most prevalent bacteria found in wounds. Staphylococcus aureus was found significantly more often in patients with chronic wounds (41; 48.8%) than in patients with acute wounds (8; 9.5%), while Staphylococcus epidermidis was found predominantly in acute wounds (15; 17.9%). At the time of study, patients with chronic wounds (58.3%) had received more antibiotic treatments in the past previous 12 months compared with patients with acute wounds (16.7%). In the antibiotic susceptibility test, Staphylococcus spp. revealed highest resistance towards penicillin and ampicillin. Isolates showed no decrease in susceptibility against a number of newly developed antibiotics (linezolid, daptomycin, and tigecycline). Conclusions: Our finding showed that bacteria diversity and antimicrobial-resistant strains are more frequently found in chronic wounds than in acute wounds.

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“…Severe manifestations and ulceration occur in 4% to 6% and 7% to 23%, respectively [7,8]. The prevalence of venous ulceration is at least 300 per 100000 and approximately 25% are due to DVT [9,10]. In the United States, skin changes and ulceration are present in 6 to 7 million and 400,000 to 500,000 people, respectively [11].…”

Section: Introductionmentioning

confidence: 99%

Pathophysiology of Post-Thrombotic Syndrome: The Effect of Recurrent Venous Thrombosis and Inherited Thrombophilia

Kreidy

2011

ISRN Vascular Medicine

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Post-thrombotic syndrome is an important chronic complication of deep vein thrombosis. This syndrome can be debilitating to patients and has a major economic impact on health care services. The pathophysiology of post-thrombotic syndrome is currently incompletely understood. Because therapeutic options for post-thrombotic syndrome are extremely limited and results are often disappointing, recognizing of the pathophysiology and risk factors of this syndrome is essential to prevent the disabling consequences of this disease. The present paper focuses on risk determinants of post-thrombotic syndrome after deep vein thrombosis. The contribution of recurrent venous thrombosis and inherited thrombophilia to the pathogenesis of this syndrome is reviewed and discussed in details.

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Chronic leg ulcers: an underestimated problem in primary health care among elderly patients.

Cited by 174 publications

References 3 publications

Úlcera de perna: um estudo de casos em Juiz de Fora-MG (Brasil) e região

Úlcera de perna: um estudo de casos em Juiz de Fora-MG (Brasil) e região

Prevalence and antibiotic susceptibility of bacteria from acute and chronic wounds in Malaysian subjects

Pathophysiology of Post-Thrombotic Syndrome: The Effect of Recurrent Venous Thrombosis and Inherited Thrombophilia

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