“…In the current literature, 2.2% of leg ulcers are considered to be skin cancer, more often BCC (75%) than SCC, and 2.4% of ulcers arising from chronic venous stasis will undergo malignant transformation (23). The incidence of BCC arising from chronic ulcerations, however, is quite low when one thinks of the vast number of these wounds encountered in everyday practice (24). Interestingly, a study of 125 cases found that 25% of patients with BCC had concomitant chronic venous stasis (25), suggesting a relationship between venous disease and BCC.…”