“…Perfusions and targeted infiltrations (interventional pain management) complete the most widely employed therapeutic options leading to an overall 30–50 % success rate [ 6 ]. Refractory cases may be considered eligible for surgical procedures such as neuroma excision and minimally invasive targeted neurectomies, which may further increase the percentage of successfully treated patients [ 10 ]. Unfortunately, these approaches are prone to recurrences and are only available in highly specialized centers.…”