Chronic kidney disease predicts atrial fibrillation in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention

Șerban, Răzvan Constantin; Șuș, Ioana; Lakatos, Eva Katalin; Demjen, Zoltan; Ceamburu, Alexandru; Fișcă, Paul Ciprian; Somkereki, Cristina; Hadadi, László; Scridon, Alina

doi:10.1080/00015385.2018.1521558

Cited by 9 publications

(16 citation statements)

References 32 publications

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“…To the best of our knowledge, the present work is the fi rst one evaluating the long-term post-PCI mortality and its predictors in an all-comers population in Romania. Patients were prospectively included in the institutional PCI Registry, and a complete 3-year follow-up was accomplished regarding cardiovascular re-or disease-related complications, such as the norefl ow phenomenon 37 or atrial fi brillation 38 in case of percutaneous coronary revascularization for STEMI. The depressed systolic function of the left ventricle was the single independent predictor of long-term cardiovascular mortality after both urgent and elective PCI.…”

Section: Discussionmentioning

confidence: 99%

Mortality predictors after percutaneous coronary intervention – a prospective single-center registry study

Hadadi¹,

Calburean²,

Grebenişan³

et al. 2020

Rom. J Cardio

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Objectives – To evaluate the predictors of three-year cardiovascular mortality after percutaneous coronary intervention (PCI) in a Romanian tertiary cardiovascular center. Methods – Consecutive patients treated by PCI in the Emergency Institute for Cardiovascular Diseases and Transplantation of Targu Mures were included prospectively in a local PCI Registry. Demographic, clinical, and procedural parameters of the patients enrolled in the year 2016 were statistically analyzed as possible predictors of three-year cardiovascular mortality post-PCI. Results – 1079 patients were included: 254 (23.5%) with ST-segment elevation acute myocardial infarction (STEMI), 278 (25.8%) with non-ST segment elevation acute coronary syndrome (NSTEACS) and 547 (50.7%) with chronic coronary syndrome (CCS). Three-year cardiovascular mortality was 20.1%, 10.8% and 5.7% after PCI for STEMI, NSTEACS and CCS, respectively. Cox proportional hazards regression evidenced as independent predictors of long-term mortality after PCI: low left ventricular ejection fraction (LVEF), renal dysfunction, presentation with cardiogenic shock or with cardiac arrest in the case of acute coronary syndromes, and the history of signifi cant valvular heart disease and low LVEF in the case of CCS (all p ≤0.01). Conclusions – Simple clinical variables but no procedural factors were the main predictors of 3-year cardiovascular mortality after PCI in this all-comers population.

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Section: Discussionmentioning

confidence: 99%

Mortality predictors after percutaneous coronary intervention – a prospective single-center registry study

Hadadi¹,

Calburean²,

Grebenişan³

et al. 2020

Rom. J Cardio

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“…Atrial fibrillation (AF) frequently complicates acute ST-elevation myocardial infarction (STEMI) (1)(2)(3). New-onset AF complicating STEMI is defined as AF occurring during the index event.…”

Section: Introductionmentioning

confidence: 99%

“…However, there is a study showing that only before AF, but not new-onset AF, is an independent predictor of adverse events in patients with STEMI (11). Many factors and mechanisms may be related to new-onset AF development in patients with STEMI (2,10). Some of these factors are excess catecholamine release or hemodynamic impairment, which is related to acute ischemia (2,4,10).…”

Section: Introductionmentioning

confidence: 99%

“…Many factors and mechanisms may be related to new-onset AF development in patients with STEMI (2,10). Some of these factors are excess catecholamine release or hemodynamic impairment, which is related to acute ischemia (2,4,10). Apart from factors directly linked to ischemia, chronic states, that is comorbidities can also influence frequent occurrence of new-onset AF in patients with STEMI, most probably through the mechanism of structural atrial remodeling present in these patients prior to the occurrence of acute ischemia (2).…”

Section: Introductionmentioning

confidence: 99%

“…Some of these factors are excess catecholamine release or hemodynamic impairment, which is related to acute ischemia (2,4,10). Apart from factors directly linked to ischemia, chronic states, that is comorbidities can also influence frequent occurrence of new-onset AF in patients with STEMI, most probably through the mechanism of structural atrial remodeling present in these patients prior to the occurrence of acute ischemia (2). It is well known that chronic kidney disease (CKD), as a global health problem, is significantly associated with a poor prognosis in patients with STEMI (1,12).…”

Section: Introductionmentioning

confidence: 99%

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Impact of kidney function on the occurrence of new-onset atrial fibrillation in patients with ST-elevation myocardial infarction

Savić¹,

Mrdović²,

Ašanin³

et al. 2021

Anatolian J Cardiol

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Objective: In this study, we aimed to examine the prognostic impact of decreased kidney function at admission on the occurrence of new-onset atrial fibrillation (AF) in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Methods: The study enrolled 3,115 consecutive patients with STEMI. Kidney function was assessed by estimation of the glomerular filtration rate (eGFR) at admission. Patients with cardiogenic shock at admission, patients on hemodialysis, and patients with a medical history of previous AF (paroxysmal, persistent, or permanent) were excluded. The follow-up period was six years. Results: New-onset AF occurred in 215 (6.9%) patients, 75 (34.9%) patients presented with AF, and 140 (65.1%) patients developed AF after pPCI. The median time of AF occurrence in patients who did not present with AF was 4.5 (interquartile range 1-25) hours after pPCI. New-onset AF was associated with a higher short-and long-term mortality. In the multiple logistic regression analysis, all stages of reduced kidney function were independent predictors for the occurrence of new-onset AF, and negative prognostic impact increased with the deterioration of kidney function: eGFR <90 mL/min/m 2 , hazard ratio (HR) 1.96, 95% confidence interval (CI) 1.42-2.89, p=0.011; eGFR 60-89 mL/min/m 2 , HR 1.54, 95% CI 1.13-2.57, p=0.045; eGFR 45-59 mL/min/m 2 -, HR 2.09, 95% CI 1.24-2.85, p=0.023; eGFR 30-44 mL/min/m 2 -, HR 2.93, 95% CI 1.64-5.29, p<0.001; eGFR 15-29 mL/min/m 2 -, HR 5.51, 95% CI 2.67-11.39, p<0.001. Conclusion: Decreased kidney function was significantly associated with the occurrence of new-onset AF, and its impact increased with the deterioration in kidney function, starting with an eGFR value of 90 mL/min/m 2 . New-onset AF was an independent predictor of long-term allcause mortality in the analyzed patients.

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Lipid Profile and New-Onset Atrial Fibrillation in Patients With Acute ST-Segment Elevation Myocardial Infarction (An Observational Study in Southwest of China)

Xue¹,

Zhou²,

Shen

et al. 2019

The American Journal of Cardiology

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Chronic kidney disease predicts atrial fibrillation in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention

Cited by 9 publications

References 32 publications

Mortality predictors after percutaneous coronary intervention – a prospective single-center registry study

Mortality predictors after percutaneous coronary intervention – a prospective single-center registry study

Impact of kidney function on the occurrence of new-onset atrial fibrillation in patients with ST-elevation myocardial infarction

Lipid Profile and New-Onset Atrial Fibrillation in Patients With Acute ST-Segment Elevation Myocardial Infarction (An Observational Study in Southwest of China)

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