Chronic kidney disease in neurogenic bladder

Sung, Bong Mo; Oh, Dong Jin; Choi, Moon Hee; Choi, Hye Sook

doi:10.1111/nep.12990

Cited by 22 publications

(24 citation statements)

References 29 publications

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“…Our last objective was to assess the evolution of renal function over time. Indeed, NULTD is associated with an increased risk of renal failure . We observed a decreased in creatinine clearance in around 20% of our patients.…”

Section: Discussionsupporting

confidence: 47%

“…Third, regarding sexual satisfaction we did not ask patients whether they were sexually active before surgery, the consequence being a possible under‐estimation of the impact of surgery on sexual satisfaction if we had only focused on sexually active patients. Fourth, renal function was assessed using serum creatinine clearance, which is less accurate than the use of Cystatin‐C clearance in this type of population who usually presents denutrition and amyotrophia . However, given the almost absence of any evolution of renal function during follow‐up, we do not believe that we have missed important renal deterioration.…”

Section: Discussionmentioning

confidence: 99%

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Impact on quality of life and sexual satisfaction of continent cystostomy with enterocystoplasty in an adult neurologic population

Ba¹,

Soustelle²,

Wagner³

et al. 2018

Neurourology and Urodynamics

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In the long-term, continent cystostomy with bladder enlargement provides great satisfaction to almost most patients. It has a strong positive impact on general and specific urinary QOL, patients' autonomy and urinary continence. In young patients a positive impact on sexuality was also noticed. These encouraging data, that need to be confirmed, constitute interesting information to provide to neurologic patients to help them deciding whether they are willing to undergo continent cystostomy surgery.

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Section: Discussionsupporting

confidence: 47%

Section: Discussionmentioning

confidence: 99%

Impact on quality of life and sexual satisfaction of continent cystostomy with enterocystoplasty in an adult neurologic population

Ba¹,

Soustelle²,

Wagner³

et al. 2018

Neurourology and Urodynamics

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show abstract

“…Cystatin C is preferred to creatinine for the early detection of renal impairment (LoE 5, GoR C1). 9,10,64 Annual transabdominal ultrasonography combined with urinalysis every 3-6 months is recommended for surveillance of the lower urinary tract (LoE 5, GoR C1). The appropriate intervals for video-UDS remain to be determined.…”

Section: Surveillancementioning

confidence: 99%

Clinical guidelines for the diagnosis and treatment of lower urinary tract dysfunction in patients with spinal cord injury

et al. 2020

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The present article is an abridged English translation of the Japanese clinical guidelines for the diagnosis and treatment of lower urinary tract dysfunction in patients with spinal cord injury updated as of July 2019. The patients are adult spinal cord injured patients with lower urinary tract dysfunction; special consideration of pediatric and elderly populations is presented separately. The target audience is healthcare providers who are engaged in the medical care of patients with spinal cord injury. The mandatory assessment includes medical history, physical examination, frequency‐volume chart, urinalysis, blood chemistry, transabdominal ultrasonography, measurement of post‐void residual urine, uroflowmetry and video‐urodynamic study. Optional assessments include questionnaires on the quality of life, renal scintigraphy and cystourethroscopy. The presence or absence of risk factors for renal damage and symptomatic urinary tract infection affects urinary management, as well as pharmacological treatments. Further treatment is recommended if the maximum conservative treatment fails to improve or prevent renal damage and symptomatic urinary tract infection. In addition, management of urinary incontinence should be considered individually in patients with risk factors for urinary incontinence and decreased quality of life.

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“…Neurogenic bladder (NB) due to myelomeningocele (MMC), with an estimated prevalence of 1/700 live births, is a condition strongly associated with multiple disturbances which, untreated, can result in progressive renal damage. This process may occur silently, and eventually leads to chronic renal failure [ 1 ]. Hence, NB patients require close monitoring to evaluate the evolution of glomerular and tubular renal function in order to rapidly diagnose and treat the worsening of renal outcome.…”

Section: Introductionmentioning

confidence: 99%

Are Tubular Injury Markers NGAL and KIM-1 Useful in Pediatric Neurogenic Bladder?

Bagińska

Korzeniecka‐Kozerska

2021

JCM

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The lack of early biomarkers of renal damage in children with neurogenic bladder (NB) prompts us to investigate the role of promising proteins: neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1). This prospective analysis was conducted on 58 children with NB and 25 healthy children. We assessed urinary levels of NGAL and KIM-1 in both groups. Age, sex, anthropometric measurements, activity assessment, renal function, and urodynamics parameters were analyzed. The differences between the median uNGAL and uKIM-1 in the NB group compared to control were recorded. However, only uNGAL levels were statistically significantly higher. Statistically significant correlation was found between gender, recurrent urinary tract infections, bladder trabeculation, its compliance, activity assessment, and uNGAL. To conclude, elevated levels of uNGAL may be considered a biomarker of tubular injury in children with NB due to MMC in contrast to uKIM-1.

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Chronic kidney disease in neurogenic bladder

Cited by 22 publications

References 29 publications

Impact on quality of life and sexual satisfaction of continent cystostomy with enterocystoplasty in an adult neurologic population

Impact on quality of life and sexual satisfaction of continent cystostomy with enterocystoplasty in an adult neurologic population

Clinical guidelines for the diagnosis and treatment of lower urinary tract dysfunction in patients with spinal cord injury

Are Tubular Injury Markers NGAL and KIM-1 Useful in Pediatric Neurogenic Bladder?

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