Chronic kidney disease, heart failure and anemia

Virani, Sean; Khosla, Amit; Levin, Adeera

doi:10.1016/s0828-282x(08)71026-2

Cited by 23 publications

(20 citation statements)

References 40 publications

(30 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Actually CRF has been already reported as an independent predictor for the mortality following TAVI by several groups [15]. A close relationship between HF and CRF has been also reported in previous report [16]. The interaction between the heart and the kidney is crucial in various physiologic systems, to control blood pressure, renal sodium and water excretion, arterial perfusion, oxygenation of tissues, and most importantly, the extracellular fluid balance, including intravascular volume; therefore, when one organ becomes dysfunctional the other organ may be affected as well [17].…”

Section: Predictive Factors Of Poor Outcome Following Tavisupporting

confidence: 76%

Impact of previous acute pulmonary oedema after transcatheter aortic valve implantation: Insight from French Aortic National CoreValve and Edwards 2 [FRANCE 2]registry

Furuta

Lellouche

Mouillet

et al. 2015

International Journal of Cardiology

View full text Add to dashboard Cite

Section: Predictive Factors Of Poor Outcome Following Tavisupporting

confidence: 76%

Impact of previous acute pulmonary oedema after transcatheter aortic valve implantation: Insight from French Aortic National CoreValve and Edwards 2 [FRANCE 2]registry

Furuta

Lellouche

Mouillet

et al. 2015

International Journal of Cardiology

View full text Add to dashboard Cite

“…Anemia is associated with CKD progression, an increased risk of developing CVD and decreased survival. 6 The anemia of CKD increases morbidity and mortality from cardiovascular complications which may lead to further deterioration of renal function and the establishment of a vicious cycle termed the cardio renal anemia syndrome. 2 In an observational study it was demonstrated that each 10 g/L drop in hemoglobin, leads to a 20%-40% increased risk of developing heart failure, LVH or mortality in those patients on long-term dialysis.…”

Section: Discussionmentioning

confidence: 99%

“…The complexity and the intricacies of the relationship between CKD, CVD and anemia however require further research. 6 …”

Section: Discussionmentioning

confidence: 99%

Prevalence of anemia and cardiovascular diseases in chronic kidney disease patients: a single tertiary care centre study

2017

View full text Add to dashboard Cite

Background: Chronic kidney disease (CKD) is recognized as a global health issue having high mortality and morbidity rates putting a substantial burden on global resources. CKD has become a recognised independent risk factor for several adverse health outcomes including cardiovascular disease (CVD). Anaemia is an anticipated consequence as renal function declines, and can develop at any stage of CKD. There is a strong association between anemia and cardiovascular complications in CKD patients and many studies have proven that anemia plays a key role in worsening CVD in CKD patients. The objective of this study was to study the prevalence of anemia and cardiovascular diseases in CKD patients and establish an association between them. Methods: This study was conducted between January 2008 and June 2008 for a period of six months at a Government tertiary referral institution in south India. During this period, all newly diagnosed cases of chronic kidney disease based on the National Kidney foundation definition were included in this study. All the patients were evaluated based on detailed history taking, clinical examination and laboratory investigations after an informed consent was obtained from them. Staging of CKD was done based on the national kidney foundation (NKF/KDIGO) staging system. GFR was estimated using the abbreviated MDRD (Modification of Diet in Renal Disease) formula. Results: Of the 333 newly diagnosed CKD patients, a large majority (264, 79.28%) of the patients in the study presented in stage 5 CKD. The mean Hb in the study was 8.42±2.20 g/dl. Anemia was present in 90.39% while 25.53% had an Hb of <7g/dl. The prevalence of anemia increased from stage 3 (66.6%) to stage 5 (94.7%) and this correlation was statistically significant (p<0.0005). 167 (50.15% ) were found to have some form of cardiovascular disease, of which 120 (71.86%) were males and 47 (28.14%) were females. 83.93% had left ventricular hypertrophy, 16.17% had ischemic heart disease and 7.78% had congestive heart failure. 56.3% of patients in the age group 41-60 years had cardiovascular disease. The correlation between cardiovascular disease and age was statistically significant (p = 0.04139). And it was found that cardiovascular disease was more common when the cause of CKD was Diabetic nephropathy (65.8%) and hypertensive nephrosclerosis (84.6%). The correlation between the cardiovascular disease and etiological diagnosis of CKD was statistically significant. (p<0.0005).Cardiovascular disease was present in 61.2 % of the study population with diabetes mellitus and in 56.4% of the study population with hypertension. The correlations between CVD and diabetes and hypertension were statistically significant. Cardiovascular disease was present in 61.2% of the study population with Hemoglobin <7 gm/dl, 41.7% with Hb between 7-11 gm/dl and the correlation between cardiovascular disease and the level of Hb was highly significant in CKD patients. Conclusions: Thus there is a strong association between the clinical trial of anemia, CK...

show abstract

“…breathlessness, ankle swelling, and fatigue) are often accompanied by equally burdening symptoms of HF co-morbidities (e.g. chronic kidney disease, anaemia) (Virani, Khosla, & Levin, 2008). Thus, HF patients experience numerous limitations in their daily activities, which is related to a significant reduction of their quality of life (Ramani, Uber, Pharm, & Mehra, 2010;Allen et al, 2011) or even to the development of depressive symptoms (Dunderdale, Thompson, Miles, Beer, & Furze, 2005).…”

Section: Discussionmentioning

confidence: 99%

Attitude towards knowledge of the disease and psychological characteristics of patients with systolic heart failure

Krzysztofik¹,

Siennicka²,

Banasiak³

et al. 2016

Health Psychology Report

View full text Add to dashboard Cite

show abstract

Chronic kidney disease, heart failure and anemia

Cited by 23 publications

References 40 publications

Impact of previous acute pulmonary oedema after transcatheter aortic valve implantation: Insight from French Aortic National CoreValve and Edwards 2 [FRANCE 2]registry

Impact of previous acute pulmonary oedema after transcatheter aortic valve implantation: Insight from French Aortic National CoreValve and Edwards 2 [FRANCE 2]registry

Prevalence of anemia and cardiovascular diseases in chronic kidney disease patients: a single tertiary care centre study

Attitude towards knowledge of the disease and psychological characteristics of patients with systolic heart failure

Contact Info

Product

Resources

About