2023
DOI: 10.1136/bmjph-2023-000235
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Chronic kidney disease and its predictors among highly active antiretroviral therapy naïve and experienced HIV-infected individuals at the selected hospitals, Southwest Ethiopia: a comparative cross-sectional study

Alemayehu Sayih Belay,
Gizachew Ayele Manaye,
Kindie Mitiku Kebede
et al.

Abstract: ObjectiveThis study aimed to determine the prevalence of chronic kidney disease (CKD) and its predictors among highly active antiretroviral therapy (HAART) naïve and experienced HIV-infected individuals.Method and analysisHospital-based comparative cross-sectional study design was used at Mizan-Tepi University Teaching Hospital, Bonga General Hospital and Tepi General Hospital. A total of 616 naïve and experienced HIV-infected individuals participated. A systematic random sampling and consecutive sampling meth… Show more

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“…Several factors, including HIV-associated nephropathy, erythropoietin deficiency, chronic inflammation, and the nephrotoxic effects of antiretroviral medications, contribute to the heightened risk of chronic kidney disease (CKD) in the presence of chronic anemia [ 106 , 107 ]. HIV-related immunosuppression and comorbidities such as opportunistic infections further amplify the impact of anemia on renal health [ 108 ].…”
Section: Chronic Anemia In Hiv Is Associated With Chronic Kidney Dise...mentioning
confidence: 99%
“…Several factors, including HIV-associated nephropathy, erythropoietin deficiency, chronic inflammation, and the nephrotoxic effects of antiretroviral medications, contribute to the heightened risk of chronic kidney disease (CKD) in the presence of chronic anemia [ 106 , 107 ]. HIV-related immunosuppression and comorbidities such as opportunistic infections further amplify the impact of anemia on renal health [ 108 ].…”
Section: Chronic Anemia In Hiv Is Associated With Chronic Kidney Dise...mentioning
confidence: 99%