Chronic Intestinal Pseudo-Obstruction Related to Viral Infections

Giorgio, Roberto De; Ricciardiello, Luigi; Naponelli, Valeria; Selgrad, Michael; Piazzi, Giulia; Felicani, Cristina; Serra, Mauro; Fronzoni, L.; Antonucci, Alexandra; Cogliandro, Rosanna; Barbara, Giovanni; Corinaldesi, Roberto; Tonini, Marcello; Knowles, Charles H.; Stanghellini, Vincenzo

doi:10.1016/j.transproceed.2009.12.014

Cited by 40 publications

(21 citation statements)

References 35 publications

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“…CIPO may also occur secondary to intestinal surgery and a range of toxins, endocrine and metabolic defects. More recently, neuropathic viruses have been implicated in adult patients with CIPO 71 .…”

Section: Pathophysiologymentioning

confidence: 99%

Gastrointestinal and nutritional problems in neurologically impaired children

Quitadamo

Thapar

Staiano

et al. 2016

European Journal of Paediatric Neurology

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Fax: + 44 20 7813 8382Gut Motility disorders comprise a heterogeneous group of disorders that result from disruption of the functional integrity of the intrinsic neuromusculature of the gastrointestinal (GI) tract. This intrinsic neuromusculature includes the smooth muscle layers, the intrinsic nervous system of the GI tract (enteric nervous system or ENS) and the interstitial cells of Cajal. The contribution of each of these components to function can be compromised by alterations in structure (ranging from absence to derangement in numbers and/or anatomy) or of function (complete or partial failure in physiological function). This pathology can be primary or secondary to a number of insults e.g. infections, inflammation, toxins etc. In children disorders may be congenital being present from birth or acquired later in life. Finally involvement of the enteric neuromusculature can be patchy/segmental or affect the gastrointestinal tract diffusely.Neuro-gastroenterology is the study of the interface of all aspects of the gastrointestinal tract or digestive system with the different branches of the body's nervous system including the enteric, central and autonomic nervous systems. The combined terms 'Neurogastroenterology and motility' are designed to encompass the study of all the components of the enteric neuromuscualture and their modulating influences and represents one of the fastest growing areas in gastroenterology clinical practice and research. This chapter aims to address some of the most common neurogastroenterology and motility conditions seen in clinical practice ranging from those with defined pathology to those which fall under the umbrella of functional gastrointestinal disorders. The latter comprise some of the commonest but challenging disorders and the term 'functional' reflects the fact that in the majority of such conditions no organic cause can be found. It should also be noted that at the present time many functional disorders e.g. abdominal pain-related functional GI disorders, represent symptom complexes that can further be subdivided into more discrete entities e.g. irritable bowel syndrome, functional abdominal pain etc depending on the nature, location and associations of the symptoms. Clinicians will often rely on the presence or absence of 'red flags' e.g. associated weight loss, severe or significant symptoms etc to decide whether patients are likely to have organic or functional disorders. Exhaustive investigations in the latter are likely to prove fruitless, expensive and perpetuate 'illness behaviours' in the patients. Abdominal pain-related functional gastrointestinal disorders IntroductionAbdominal pain-related functional gastrointestinal disorders (FGID) constitute a spectrum of conditions characterised by the presence of recurrent abdominal pain in the absence of any defined pathology 1 . In the past these disorders fell under the single term 'Recurrent abdominal pain' (RAP) but have since been recategorised under an international initiative (Rome Foundation) to improve the dia...

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Section: Pathophysiologymentioning

confidence: 99%

Gastrointestinal and nutritional problems in neurologically impaired children

Quitadamo

Thapar

Staiano

et al. 2016

European Journal of Paediatric Neurology

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“…The idiopathic form of inflammatory degenerative ENS neuropathy is unrelated to neoplasms, infectious conditions, or other known diseases [61][62][63][64][65][66]. On the other hand, the varicella-zoster virus (i.e., chickenpox) establishes latency in ENS neurons and can reactivate to lyse and kill the neurons within 48 h of infection [54,55,[67][68][69].…”

Section: Non-inflammatory Degenerative Neuropathymentioning

confidence: 99%

Enteric Nervous System: Neuropathic Gastrointestinal Motility

Wood

2016

Dig Dis Sci

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“…It can involve any part of the gastrointestinal system and is classified into either primary or secondary forms. The primary, or congenital, form is more prevalent in children, whereas the secondary, or acquired, form is more prevalent in adults [5][6][7]. Gastrointestinal system, smooth muscle, nervous system and endocrine system impairments, metabolic and autoimmune disorders, and infectious states (CMV, EBV, etc.)…”

Section: Discussionmentioning

confidence: 99%

“…Gastrointestinal system, smooth muscle, nervous system and endocrine system impairments, metabolic and autoimmune disorders, and infectious states (CMV, EBV, etc.) are among the secondary causes [1,7]. The disorder is termed as chronic idiopathic intestinal pseudo-obstruction (CIIP), should it not be attributed to any genetic or secondary cause [4].…”

Section: Discussionmentioning

confidence: 99%

Chronic intestinal pseudo-obstruction: Report of two cases

Akbulut¹,

Topal²,

Savas³

et al. 2013

CMJ

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Chronic intestinal pseudo-obstruction is a rare intestinal motility disorder. It is characterized by recurrent or persistent findings of intestinal obstruction in the absence of any mechanical obstruction. Various systemic or congenital diseases are held responsible in the etiology; moreover, it is accepted as idiopathic upon failure of detection of a true reason. We present hereby two rare cases who had been admitted with the symptoms of nausea, vomiting, constipation and tetany, and were diagnosed as chronic intestinal pseudo-obstruction.

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Chronic Intestinal Pseudo-Obstruction Related to Viral Infections

Cited by 40 publications

References 35 publications

Gastrointestinal and nutritional problems in neurologically impaired children

Gastrointestinal and nutritional problems in neurologically impaired children

Enteric Nervous System: Neuropathic Gastrointestinal Motility

Chronic intestinal pseudo-obstruction: Report of two cases

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