2014
DOI: 10.7243/2052-5958-2-3
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Chronic infections: causes and possible approach to treatment

Abstract: The mechanisms of chronic infectious diseases remain poorly understood, and optimal methods for their treatment are still to be found. An attempt is made to analyze available data by analogy with natural chronic foci of normal microflora, which are useful and even necessary to the host. The analogy is justified because both normal and pathogenic infective microfloras are basically similar in their essential characteristics, such as contagiousness, conditional pathogenicity, the possibility of healthy carriage,… Show more

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Cited by 4 publications
(4 citation statements)
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“…Only infectious microorganisms cause chronic infections. e normal micro ora is the most infectious microorganism, with all species becoming infected immediately a er birth because this micro ora is permanently required by the host (Malyshkin, 2014).…”
Section: Discussionmentioning
confidence: 99%
“…Only infectious microorganisms cause chronic infections. e normal micro ora is the most infectious microorganism, with all species becoming infected immediately a er birth because this micro ora is permanently required by the host (Malyshkin, 2014).…”
Section: Discussionmentioning
confidence: 99%
“…Meetoo [3] notes that chronic noncommunicable diseases are the leading causes of death in most of the industrialized countries, and despite the burden from these diseases globally, the responses and the efforts geared towards preventing them have been slow, both nationally and worldwide. Chronic diseases are the main worry for community/public health [17].…”
Section: Chronic Diseases' Burdensmentioning
confidence: 99%
“…This explanation, however, seems insufficient. There are grounds to believe that the necessity of interaction with microorganisms stems from the usefulness of microbial activities per se rather than immune stimulation [1]. For example, the normal intestinal microflora, which is the most necessary microbial community of the human body, synthesizes vitamins, contributes to food digestion, etc.…”
Section: Correspondencementioning
confidence: 99%
“…The development of disease prevention and treatment strategies in the context of the hygiene hypothesis requires identification of the ambient microorganisms that are essential for normal human physiological functions. Given the wide diversity of microorganisms, this is a difficult task; however, the search can be narrowed down by considering that the necessary microorganisms can only be found among infective ones [1].…”
Section: Correspondencementioning
confidence: 99%