Chronic haematogenous osteomyelitis in children

Abstract

From a global point of view, chronic haematogenous osteomyelitis in children remains a major cause of musculoskeletal morbidity. We have reviewed the literature with the aim of estimating the scale of the problem and summarising the existing research, including that from our institution. We have highlighted areas where well-conducted research might improve our understanding of this condition and its treatment.

Challenges in managing paediatric osteomyelitis in the developing world: Analysis of cases presenting to a tertiary referral centre in Tanzania

“…It is, to our knowledge, the second largest epidemiological study of paediatric osteomyelitis in the developing world. [1] The patient group affected were predominantly males (73%) with a mean age of 11 years, and the most commonly affected sites were the tibia and femur, in keeping with comparable studies elsewhere in Africa. [8][9][10] In the majority of cases (89%), there was no relevant history of trauma and infection was presumed to be haematogenous in origin.…”

“…[1,2] In a review of surgical procedures in Uganda, 3.5% were performed for osteomyelitis, [3] and of children under the age of 15 admitted to a government referral hospital in the Gambia, osteomyelitis accounted for 15.4% of inpatient days, more than for any other diagnosis except burns. [4] Delay in the presentation and treatment of acute osteomyelitis due to a lack of availability of primary and secondary healthcare services often results in progression to chronic disease with associated morbidity.…”

“…[5,6] The literature on paediatric osteomyelitis in the developing world is scarce, and there have been calls for further characterisation of its epidemiology and the identification of local factors that limit effective management in order to guide local service delivery. [1] Kilimanjaro Christian Medical Centre (KCMC) is a tertiary referral centre for a population of 11 million people in Northern Tanzania and contains a specialist orthopaedic department. Our aims were to characterise ABSTRACT Background: The literature on paediatric osteomyelitis in the developing world is scarce, and there have been calls for further characterisation of its epidemiology and the identification of factors that limit effective management in order to guide local service delivery.…”

Osteomyelitis

“…The Beit CURE classifi cation [ 14 ] is a radiological classifi cation that is useful in the surgical planning of disease. Though less well known than the Cierny-Mader classifi cation [ 15 ], it has been developed specifi cally for use in resourcepoor environments and is a valuable tool in surgical planning as well as comparative research.…”

Ikterus, Anämie, akutes Abdomen

“…funktionellen Asplenie ("Autosplenektomie") mit entsprechend gehäuften Infekten. Im Skelettbereich sind die Verschlüs-se häufig Ausgangspunkt von Osteomyelitiden, die oft durch Salmonellen ausgelöst werden [5]. Neben Funktionseinschrän-kungen in den Gelenken infolge asep- …”