2022
DOI: 10.2147/vhrm.s371468
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Chronic Fatigue Associated with Post-COVID Syndrome versus Transient Fatigue Caused by High-Intensity Exercise: Are They Comparable in Terms of Vascular Effects?

Abstract: Purpose The pathophysiology of chronic fatigue associated with post-COVID syndrome is not well recognized. It is assumed that this condition is partly due to vascular dysfunction developed during an acute phase of infection. There is great demand for a diagnostic tool that is able to clinically assess post-COVID syndrome and monitor the rehabilitation process. Patients and Methods The Flow Mediated Skin Fluorescence (FMSF) technique appears uniquely suitable for the ana… Show more

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Cited by 7 publications
(14 citation statements)
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“…The results of this study and the results presented in reference 4 for stress due to physical exhaustion and viral infection suggest that the NOI parameter can be used to evaluate stress of any origin. However, some distinctive differences were noticed.…”
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confidence: 59%
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“…The results of this study and the results presented in reference 4 for stress due to physical exhaustion and viral infection suggest that the NOI parameter can be used to evaluate stress of any origin. However, some distinctive differences were noticed.…”
mentioning
confidence: 59%
“…Very recently, we showed that chronic fatigue associated with post-COVID syndrome and transient fatigue caused by high-intensity exercise are comparable in terms of vascular effects. 4 The analysis of microcirculation oscillations detected at rest using the Flow Mediated Skin Fluorescence (FMSF) technique can be of particular use for monitoring physical stress related to strenuous exercise or post-infection fatigue. It is rational to assume that a similar methodology can be applied to assess the vascular consequences of psychological stress.…”
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confidence: 99%
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“…One such exception may be the analysis of the flowmotion at rest, especially the relative ratio of endothelial and neurogenic oscillations to myogenic oscillations. Thus, a new parameter representing the contribution of endothelial and neurogenic oscillations relative to all oscillations detected at low frequency intervals (<0.15 Hz) can be introduced [ 45 ]: NOI = [PSD(endothelial) + PSD (neurogenic)]/[PSD(endothelial) + PSD (neurogenic) + PSD(myogenic)] × 100% …”
Section: Definition Of the Measured Fmsf Parametersmentioning
confidence: 99%
“…One such exception may be the analysis of the flowmotion at rest, especially the relative ratio of endothelial and neurogenic oscillations to myogenic oscillations. Thus, a new parameter representing the contribution of endothelial and neurogenic oscillations relative to all oscillations detected at low frequency intervals (< 0.15 Hz) can be introduced [45]: NOI = [PSD(endothelial) + PSD (neurogenic)]/[PSD(endothelial) + PSD (neurogenic) + PSD(myogenic)] × 100% Despite of the decrease of flowmotion (FM) at rest with age, the NOI parameter remains age independent. Moreover, in patients with some diseases affecting the vascular system and thus also basal flowmotion, such as diabetes mellitus (group C -diabetes type-2 patients, n = 70 (40 m, 32 f), mean age 63.1 (45-80 y.…”
Section: Hypoxia Sensitivity (Hs)mentioning
confidence: 99%