Chronic Exposure to Extremely Low Frequency Electromagnetic Field Induces Mild Renal Damages in Rats

Gholampour, Firouzeh; Owji, Seyed Mohammad; Javadifar, Tahereh Sadat

doi:10.3923/ijzr.2011.393.400

Cited by 8 publications

(3 citation statements)

References 17 publications

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“…Renal is a main probable path for imbibing of risky substances occurred in the environment [21] . It was chosen in this study because it is a very vital organ for healthy life of mammals.…”

Section: Discussionmentioning

confidence: 99%

Carisoprodol (Somadril) induced histological and histochemical changes in renal cortex of pregnant rats and their fetuses

Abdelhafez

Rabou

2019

Egyptian Journal of Histology

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Background: Carisoprodol is a generally prescribed skeletal muscle relaxant whose primary active metabolite is meprobamate, a substance with well-established abuse potential similar to that of benzodiazepines. A number of reports showed that carisoprodol has been abused for its anodyne and relaxant effects. Aim: The diversion and misuse of carisoprodol and its adverse health effects appeared to be dramatically increased over the last several years. This study aimed to detect the histological and histochemical changes in the cortex of renal tissue of pregnant rats and their fetuses after treatment with carisoprodol. Materials and Methods: Thirty pregnant female rats were randomly categorized into three groups (ten pregnant female rats in each group). The first was administered oral doses of distilled water and served as control. The other two groups were administered oral doses of carisoprodol (Somadril compound) in the distilled water equivalent to 10.8 and 21.6 mg/100g body weight/day respectively for 15 days from the 6 th day to the 20 th day of gestation. Results: Maternal and fetal renal cortex tissue of both treated groups showed lots of degenerative changes post-treatment with carisoprodol. The severity of these changes was more obvious in fetal cortex of renal tissue of both groups this was accompanied with numerous histochemical changes. Conclusion: Treatment of pregnant rats with carisoprodol led to numerous dystrophic changes in the maternal and fetal renal cortex tissue. These findings provide evidence to support current recommendations to avoid the use of carisoprodol in pregnant rats except if the potential benefit justifies the risk to the fetuses.

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“…Renal is a main probable path for imbibing of risky substances occurred in the environment [21] . It was chosen in this study because it is a very vital organ for healthy life of mammals.…”

Section: Discussionmentioning

confidence: 99%

Carisoprodol (Somadril) induced histological and histochemical changes in renal cortex of pregnant rats and their fetuses

Abdelhafez

Rabou

2019

Egyptian Journal of Histology

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“…The effects of EMF-IF on the incidence of diseases of the genitourinary system were detected in electricians with experimental confirmation of changes in kidney function, which led to an increase in creatinine and urea concentrations in blood plasma (p<0.001), accompanied by severe vascular stasis in the renal cortex and a decrease in the number of erythrocytes in the glomerular capillaries [6]. The experiment also showed that longterm exposure to EMF could lead to oxidative damage to the liver and spleen with an increase in alanine aminotransferase (ALT) and aspartate aminotransferase (AST), and a decrease in glutathione peroxidase and superoxide dismutase, along with serum immunoglobulins [7].…”

Section: Resultsmentioning

confidence: 89%

Evaluating Occupational Morbidity Among Energy Enterprise Employees In Industrial Region Of Kazakhstan

et al. 2021

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Our research project was aimed at studying the effects of an electromagnetic field of industrial frequency (EMF-IF) on employees of an energy company in Kazakhstan. Material and Methods — The object of our study was the health status of electricians (morbidity with temporary disability – MTD), engaged in the maintenance of power lines, relay protection systems and substations (220 and 500 kV) at an energy enterprise in Kazakhstan. The interrelation and dependence of the intensive MTD indicators on the hygienic factors at the workplace were determined, and the risks were calculated from the obtained data. Results — Unfavorable workplace conditions caused an increase in disorders of the musculoskeletal system (up to 77%), blood circulation (up to 65%), nervous system (up to 52%), skin diseases (up to 46.4%), as well as the manifold rise of the likelihood of neoplasm growth and respiratory diseases. For electricians, the relationships between the nervous system disorders (r=0.792), the circulatory system diseases (r=0.573), the musculoskeletal system ailments (r=0.672) and the EMF-IF parameters were discovered. At the same time, the dependence of the incidence rates of various diseases in workers on EMF, as well as moderate to high computed relative risks, implied the occupational genesis of worklace ailments: for nervous system – R2=0.628, cardiovascular system – R2=0.709, skin – R2=0.729, and musculoskeletal system – R2=0.413. Conclusion — As preventive measures for electricians, we recommended to wear individual exposure meters, to limit work in contact with EMF, to include an oncologist in the medical commission, and for trainees, to screen for oxidative stress proteins and chaperone proteins to exclude a predisposition to oncogenesis.

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“…We can categorize electromagnetic sources into two groups: natural electromagnetic sources (atmospheric discharges like thunder, sun, some distant stars or human body) and unnatural or human made sources (printers, vacuum cleaners, cell phones, hair dryers, microwaves) [11] [12], electrical home equipment, computers, cables that carry electrical currents, Television [13], radio and TV base stations, mobile phone base stations and phone equipment [14] [15]. A lot of investigations have carried out to evaluate the effects of electromagnetic fields on human health, histologically and also physiologically [7] [8] [9] [16] [17] [18] [19].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Distance and Duration of Exposure to Electromagnetic Radiation of Hair Dryer on Rat Sperm Parameters

Safari¹,

Mortazavi²,

Aghazade³

et al. 2020

JBM

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Chronic Exposure to Extremely Low Frequency Electromagnetic Field Induces Mild Renal Damages in Rats

Cited by 8 publications

References 17 publications

Carisoprodol (Somadril) induced histological and histochemical changes in renal cortex of pregnant rats and their fetuses

Carisoprodol (Somadril) induced histological and histochemical changes in renal cortex of pregnant rats and their fetuses

Evaluating Occupational Morbidity Among Energy Enterprise Employees In Industrial Region Of Kazakhstan

The Effects of Distance and Duration of Exposure to Electromagnetic Radiation of Hair Dryer on Rat Sperm Parameters

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