Chronic exposure of coho salmon to sublethal concentrations of copper—I. Effect on growth, on accumulation and distribution of copper, and on copper tolerance

Buckley, J. Thomas; Roch, M.; McCarter, J. A.; Rendell, C.A.; Matheson, A. T.

doi:10.1016/0306-4492(82)90198-8

Cited by 89 publications

(63 citation statements)

References 9 publications

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“…This is an indication that the ensuing increased availability of non-MT metal-binding proteins in the liver resulted in uptake of excess Zn, which entered the bloodstream through the gill tissue. Stimulation of Zn uptake by liver tissue following Cd and Cu exposure was also recorded by Noël-Lambot et al (1978) and Buckley et al (1982). The increased uptake of Zn in the presence of other metals can most likely also be attributed to the proposed stress-response mechanism, which liberates and depurates metals from metal-binding proteins in the liver, thus providing available proteins for the binding of excess metals.…”

Section: Metal Uptake By the Livermentioning

confidence: 91%

Uptake and distribution of a copper, iron and zinc mixture in gill, liver and plasma of a freshwater teleost, <i>Tilapia sparrmanii</i>

Wepener¹,

Vuren²,

Preez³

2004

WSA

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Since polluted environments contain mixtures of different contaminants, the aim of this study was to investigate the time-integrated uptake of individual metals by a freshwater teleost, Tilapia sparrmanii following exposure to a metal mixture containing Cu, Fe and Zn. The metal concentrations used during the bioassays were chosen to represent ecologically relevant concentrations as found in the Olifants River, Kruger National Park, South Africa. The concentrations used in the bioassay were 0.16 mg·l -1 , 4.3 mg·l -1 and 1.003 mg·l -1 for Cu, Fe and Zn respectively. Gill, plasma and liver were sampled at 0, 2, 4, 6, 12, 24, 24, 48, 72, 96 h and four weeks. Gill tissue is the initial site of accumulation of water-borne metals. Although the fish were exposed to a metal mixture, the interactions between metals and the external gill surface, as well as the subsequent uptake rate, were associated with the particular chemical properties of individual metals. The tendency of the individual metals in the metal mixture to bind to the external gill surface via ionic bonds, and to gill cytosolic compounds via covalent bonds, was Cu > Fe > Zn. The ensuing uptake rates into the extracellular compartment (blood) and intracellular compartment (liver tissue) were Zn > Fe > Cu. The toxic effects of Cu and Fe were, therefore, primarily exerted on the gill surface and in the gill cytosol, whereas the toxic action of Zn was primarily limited to the internal organs.

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Section: Metal Uptake By the Livermentioning

confidence: 91%

Uptake and distribution of a copper, iron and zinc mixture in gill, liver and plasma of a freshwater teleost, <i>Tilapia sparrmanii</i>

Wepener¹,

Vuren²,

Preez³

2004

WSA

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“…Cu, as an essential metal, plays an important role in cellular metabolism (Cousins, 1985) and its concentration is well regulated. However, exposure of fish to increased Cu concentrations results in Cu accumulation (Brungs et al, 1973;Buckley et al, 1982). As a result, various blood parameters (McKim et al, 1970;Christensen et al, 1972), enzyme activities in blood (Christensen and Tucker, 1976) and reproduction (Homing and Nieheisel, 1979) are affected.…”

Section: Introductionmentioning

confidence: 99%

Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus

Pelgrom

Lamers

Lock

et al. 1995

Environmental Pollution

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“…Accumulation of copper has also been seen in gill and kidney tissue from the brown bullhead catfish (Ameiurus nebulosus) [3], bluegill (Lepomis macrochirus) [2] and coho salmon (Oncorhynchus kisutch) [4]. The organs of aquatic animals accumulate copper, which may cause morphological alterations and change certain physiological processes [24].…”

mentioning

confidence: 99%

Acute and Subacute Toxicity of Copper Sulfate Pentahydrate (CuSO45 H2O) in the Guppy (Poecilia reticulata)

Park

Heo

2009

J. Vet. Med. Sci.

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ABSTRACT. Chemicals are used for treatment of aquatic diseases, but there is little data available about copper sulfate in small ornamental fish. The aim of the present study was to determine the TLm 24h and evaluate the toxicity of copper sulfate in the guppy (Poecilia reticulata). The fish were subjected to an acute toxicity test for 24 hr, and the results showed a TLm 24h value of 1.17 ppm. Severe hyperplasia and exfoliation of the epithelial cells of gill lamellae and obstruction of the internal cavities of renal tubules with necrotized renal epithelial cells sloughed from the basement membrane were observed. However, no significant changes, except for mild curling of gill lamellae, were found in a subacute toxicity test in which fish were exposed to 1/10 of the TLm 24h value for 1 week. Therefore, use of less than 0.12 ppm of copper sulfate may be recommended as a therapeutic level.

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Chronic exposure of coho salmon to sublethal concentrations of copper—I. Effect on growth, on accumulation and distribution of copper, and on copper tolerance

Cited by 89 publications

References 9 publications

Uptake and distribution of a copper, iron and zinc mixture in gill, liver and plasma of a freshwater teleost, <i>Tilapia sparrmanii</i>

Uptake and distribution of a copper, iron and zinc mixture in gill, liver and plasma of a freshwater teleost, <i>Tilapia sparrmanii</i>

Interactions between copper and cadmium modify metal organ distribution in mature tilapia, Oreochromis mossambicus

Acute and Subacute Toxicity of Copper Sulfate Pentahydrate (CuSO45 H2O) in the Guppy (Poecilia reticulata)

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