Chronic effects of a binary insecticide Acer 35 EC on Nile tilapia Oreochromis niloticus through a multi-biomarker approach

Abstract

h i g h l i g h t s Even at doses below the environmental concentrations, Acer 35 EC impairs the physiology and health status of Nile tilapia. Acer 35 EC affects many systems including immune, reproductive and nervous systems. The adverse effects of Acer 35 EC are dependent on time and sex. Insecticide Acer 35 EC affects females more than males.

Exposure to neonicotinoids and serum testosterone in men, women, and children

“…This was observed in ICR male mice exposed to 3, 10, and 30 mg/L in drinking water for 10 weeks and in male Wistar rats orally exposed to 45 and 90 mg/kg or 0.5–8 mg/kg for 90 days 7,21,22 . Our results suggested that reduced testosterone associated with neonicotinoid exposure may occur not only in males, but also in females and this was noted in female Nile tilapia exposed to acetamiprid mixed with a pyrethroids 23 . We found that the association of N ‐desmethyl‐acetamiprid with lower serum total testosterone among females was dependent on age and was observed in women aged 40 years or older.…”

“…7,21,22 Our results suggested that reduced testosterone associated with neonicotinoid exposure may occur not only in males, but also in females and this was noted in female Nile tilapia exposed to acetamiprid mixed with a pyrethroids. 23 We found that the association of N-desmethyl-acetamiprid with lower serum total testosterone among females was dependent on age and was observed in women aged 40 years or older. Two animal studies also showed that the effects of acetamiprid and imidacloprid on the reproductive system may be more pronounced in mature than in immature rodents.…”