Chronic diseases influence major life changing decisions: a new domain in quality of life research

Bhatti, Zaheer Uddin; Salek, Mir-saeed; Finlay, A.Y.

doi:10.1258/jrsm.2011.110010

Cited by 40 publications

(55 citation statements)

References 58 publications

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“…There are many published surveys assessing the impact of chronic diseases on patients' QoL. However, these studies have not addressed the long-term impact of chronic diseases on critical life decisions taken by patients [12]. …”

Section: Quality Of Lifementioning

confidence: 99%

“…Even follow-up studies, which might be expected to encompass more long-term issues, usually compare current impacts before and after a given intervention. In the study by Bhatti et al [12], adult dermatology patients explained how their chronic disease had influenced major life-changing decisions. The authors evaluated 308 responses (mean age 51.8 years, mean disease duration 19 years).…”

Section: Quality Of Lifementioning

confidence: 99%

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The Impact of Atopic Dermatitis on Quality of Life

Lifschitz¹

2015

Ann Nutr Metab

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Approximately 5-20% of children worldwide suffer from atopic dermatitis (AD), a kind of dermatitis characterized as an inflammatory, relapsing, noncontagious and itchy skin disorder. Children often develop AD during their first year of life. An increased rate of sensitization to both food and aeroallergens has been shown to coexist in patients with AD. Sensitization to well-known allergens such as cow's milk protein can occur on average in 50% of children with AD. In general, quality of life (QoL) is perceived as the quality of an individual's daily life, that is, an assessment of their well-being or lack thereof. QoL is a broad concept that includes such things as standard of living, community, and family life. Patients with skin diseases experience a wide range of symptoms ranging from trivial problems to major handicaps which affect their lives. The misery of living with AD cannot be overstated for it may have a profoundly negative effect on the health-related QoL of children and their families in many cases. Physicians taking care of children with AD should consult parents on how their child's illness has impacted their lifestyle and recommend professional intervention if deemed necessary.

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Section: Quality Of Lifementioning

confidence: 99%

Section: Quality Of Lifementioning

confidence: 99%

The Impact of Atopic Dermatitis on Quality of Life

Lifschitz¹

2015

Ann Nutr Metab

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“…However disease may have an additional major long-term impact by influencing major life changing decisions (MLCDs) [1,2], such as those concerning education, career, relationships or having children [3-7]. …”

Section: Introductionmentioning

confidence: 99%

The development and validation of the major life changing decision profile (MLCDP)

Bhatti

Salek

Bolton

et al. 2013

Health and Quality of Life Outcomes

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BackgroundChronic diseases may influence patients taking major life changing decisions (MLCDs) concerning for example education, career, relationships, having children and retirement. A validated measure is needed to evaluate the impact of chronic diseases on MLCDs, improving assessment of their life-long burden. The aims of this study were to develop a validated questionnaire, the “Major Life Changing Decision Profile” (MLCDP) and to evaluate its psychometric properties.Methods50 interviews with dermatology patients and 258 questionnaires, completed by cardiology, rheumatology, nephrology, diabetes and respiratory disorder patients, were analysed for qualitative data using Nvivo8 software. Content validation was carried out by a panel of experts. The first version of the MLCDP was completed by 210 patients and an iterative process of multiple Exploratory Factor Analyses and item prevalence was used to guide item reduction. Face validity and practicability was assessed by patients.Results48 MLCDs were selected from analysis of the transcripts and questionnaires for the first version of the MLCDP, and reduced to 45 by combination of similar themes. There was a high intraclass correlation coefficient (0.7) between the 13 members of the content validation panel. Four more items were deleted leaving a 41-item MLCDP that was completed by 210 patients. The most frequently recorded MLCDs were decisions to change eating habits (71.4%), to change smoking/drinking alcohol habits (58.5%) and not to travel or go for holidays abroad (50.9%).Factor analysis suggested item number reduction from 41 to 34, to 29, then 23 items. However after taking into account item prevalence data as well as factor analysis results, 32 items were retained. The 32-item MLCDP has five domains education (3 items), job/career (9), family/relationships (5), social (10) and physical (5). The MLCDP score is expressed as the absolute number of decisions that have been affected.ConclusionsThe 32-item (5 domains) MLCDP has been developed as an easy to complete generic tool for use in clinical practice and for quality of life and epidemiological research. Further validation is required.

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“…Bhatti et al (2011) reported about the impact of chronic diseases on major life changing decisions like marriage, divorce, childbearing etc. It is suggested that the poor health from a spouse at a young age may cause marriage breakup over time.…”

Section: Partnershipmentioning

confidence: 99%

“…It is suggested that the poor health from a spouse at a young age may cause marriage breakup over time. For a couple with early stage disease and the option of fertility sparing surgery, the decision to intend to have a child is difficult due to the fear of recurrence (Bhatti et al 2011). Glantz et al (2009) described that the risk of being abandoned by the partner after surviving a severe disease is especially higher for women (20.8%) than for men (2.9%).…”

Section: Partnershipmentioning

confidence: 99%