Chronic cutaneous mycobacterial ulcers due to Mycobacterium ulcerans (Buruli ulcer): the first indigenous case report from Jordan and a literature review

Abstract

An indigenous case of M. ulcerans (Buruli ulcer) is reported for the first time from Jordan and the surrounding region.

From hidden outbreaks to epidemic emergencies: the threat associated with neglecting emerging pathogens

“…The bacterium and associated disease has subsequently been found in several other areas of Africa including Angola [71], Benin [72], the Democratic Republic of the Congo [71], Côte D'Ivoire [73], Ghana [74], Nigeria [75], and Togo [76]. The infection also has been identified in Australia [77], and most recently Jordan [78]. While the association between the bacterium and the symptoms are well established, the mode of transmission has yet to be elucidated.…”

Experiences of Buruli Ulcer Patients Following Discharge in the Greater Accra Region of Ghana

“…Buruli ulcer (BU) is one of the skin diseases that causes physical deformity, loss of function of the affected part, social stigmatization, and financial burden to individuals affected. [1][2][3][4][5][6] Annually, an approximated 6000 cases of BU are reported worldwide especially from West Africa, Central Africa, and Asia. 7,8 Other geographical areas involved are Australia, Japan, and sporadic cases in central and South America.…”

“…Buruli ulcer is linked to a bacteria known as Mycobacterium ulcerans and is said to affect the subcutaneous tissues of the skin. [3][4][5][6] It begins as a painless nodule or papule that may later progress to massive skin ulceration if left untreated and may progress to serious complications such as contractures and deformities. 12,20 BU results in local signs and systematic symptoms such as fever, malaise, or adenopathy.…”