Chronic cor pulmonale as a complication of fibrocystic disease of the pancreas

Tomlin, Clyde E.; Logue, R. Bruce; Hurst, J. Willis

doi:10.1016/0002-8703(52)90170-1

Cited by 13 publications

(4 citation statements)

References 10 publications

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“…RV systolic function has not been systematically investigated in patients with bronchiectasis. Tomlin et al 17 19,20 of patients with cystic fibrosis showed disparate RV dysfunction rates of 0% and 72%. Koelling et al 8 observed that RV systolic function at rest and after peak exercise was similarly compromised in 40 patients with advanced cystic fibrosis, as well as in 9 patients with moderately severe bronchiectasis.…”

Section: Discussionmentioning

confidence: 98%

Right and Left Ventricular Function and Pulmonary Artery Pressure in Patients With Bronchiectasis

Alzeer

Al-Mobeirek

Al-Otair

et al. 2008

Chest

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Section: Discussionmentioning

confidence: 98%

Right and Left Ventricular Function and Pulmonary Artery Pressure in Patients With Bronchiectasis

Alzeer

Al-Mobeirek

Al-Otair

et al. 2008

Chest

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“…Although right ventricular dysfunction in patients with cystic fibrosis has been described by previous investigators, [3][4][5][6]14 left ventricular function has not been studied extensively. Tomlin et al 15 described chronic cor pulmonale as a complication of fibrocystic disease of the pancreas in 1952. Allen et al, 16 using echocardiography, identified increased right ventricular wall thickness and cavity size in 37 children with cystic fibrosis, observing that these abnormalities occurred in patients with mild as well as severe disease.…”

Section: Ventricular Dysfunction In Patients With Cystic Fibrosismentioning

confidence: 99%

Left Ventricular Diastolic Function in Patients With Advanced Cystic Fibrosis

Koelling

Dec

Ginns

et al. 2003

Chest

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“…RV systolic dysfunction was observed in patients with cystic bronchiectasis. Tomlin et al described chronic corpulmonale as a complication of fibrocystic disease of the pancreas in 1952 [25]. Vizza et al examined RV and LV function in patients with severe airway, parenchymal, and pulmonary vessel disease; the presence of RV dysfunction varied between 59% and 94% [26].…”

Section: Figurementioning

confidence: 99%

Role of a diagnostic triad in bronchiectasis

Hassan

Shalan

Allah

et al. 2015

Egyptian Journal of Chest Diseases and Tuberculosis

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Objective: To differentiate cystic and cylindrical bronchiectasis utilizing a diagnostic triad of HRCT score, PFTs, and echocardiography.Design: A prospective observational cross sectional study. Setting: All bronchiectasis patients admitted to the chest department of Assiut and Al-Azhar Universities from May 2012 to June 2014 were enrolled in this study.Main outcome measures: HRCT score, pulmonary function tests parameters (FEV1, FEV1/ FVC, FVC, PaO 2 , PaCO 2 and DLCO) and complete echocardiographic assessment were done for all patients.Results: Obstructive pulmonary defect was observed in a majority of patients (56%). FVC%, FEV1 and FEV1/FVC were lower in patients with cylindrical as compared to cystic bronchiectasis. RV diameter was significantly greater in cystic bronchiectasis, and was positively correlated with pulmonary hypertension and negatively correlated with PaO 2 . PH was significantly greater in patients with cystic bronchiectasis and was positively correlated with PaCO 2 , and inversely correlated with PaO 2 , and FEV1. Global HRCT scores for cystic bronchiectasis were significantly correlated with the values of FEV1% and with SPAP.Conclusions: Cystic bronchiectasis is associated with more severe lung function impairment and worse HRCT scores as compared with cylindrical bronchiectasis. In cystic bronchiectasis, HRCT scores correlated with FEV1% and SPAP and could be a predictor of future PH. HRCT depicts these pathological changes, moreover, high HRCT score not only reflects lung damage in those patients, but it can also be correlated with PH. PH; therefore can be a marker of lung damage in bronchiectatic patients. ª 2015 Production and hosting by Elsevier B.V. on behalf of The Egyptian Society of Chest Diseases and Tuberculosis. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).

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Chronic cor pulmonale as a complication of fibrocystic disease of the pancreas

Cited by 13 publications

References 10 publications

Right and Left Ventricular Function and Pulmonary Artery Pressure in Patients With Bronchiectasis

Right and Left Ventricular Function and Pulmonary Artery Pressure in Patients With Bronchiectasis

Left Ventricular Diastolic Function in Patients With Advanced Cystic Fibrosis

Role of a diagnostic triad in bronchiectasis

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