Chronic cicatrising conjunctivitis in a patient with hemifacial cutaneous tuberculosis

Pommier, S.; Chazalon, E.; Morand, Jean‐Jacques; Meyer, F. W.

doi:10.1136/bjo.2007.132340

Cited by 6 publications

(6 citation statements)

References 6 publications

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“…Conjunctival TB may present as conjunctivitis, subconjunctival nodules, polyps, tuberculomas, or ulcers (Figs. 5 and 6) [39], [40], [41], [42], [43], [44], [45], [46], [47]. While conjunctival involvement is more common in the setting of systemic disease, isolated conjunctivitis without systemic findings has been reported [48].…”

Section: Review Of the Literaturementioning

confidence: 99%

Orbital and external ocular manifestations of Mycobacterium tuberculosis: A review of the literature

Dalvin

Smith

2016

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis that most commonly affects the lungs. However, extrapulmonary manifestations of TB can affect the eye and surrounding orbital tissues. TB can affect nearly any tissue in the eye, and a high index of suspicion is required for accurate diagnosis. Systemic anti-tuberculosis treatment is required in cases of ocular TB, and steroids are sometimes necessary to prevent tissue damage secondary to inflammation. Delays in diagnosis are common and can result in morbidities such as loss of an affected eye. It is important for ophthalmologists and infectious disease specialists to work together to accurately diagnose and treat ocular TB in order to prevent vision loss. This article reports the various known presentations of orbital and external ocular TB and reviews important elements of diagnosis and treatment.

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Section: Review Of the Literaturementioning

confidence: 99%

Orbital and external ocular manifestations of Mycobacterium tuberculosis: A review of the literature

Dalvin

Smith

2016

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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“…Only 4 cases of conjunctival tuberculosis have been reported from the WHO European region in last 5 decades. Three of the cases were diagnosed with 10,11,12,13 primary conjunctival tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

Primary Conjunctival Tuberculosis: A Case Report

Chahar¹,

S²,

Suman³

et al. 2020

ijsr

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A 11 year old female was referred from ophthalmology clinic to pulmonary medicine department for further evaluation of a case of unilateral conjunctivitis not responding to treatment as suspected case of conjuctival tuberculosis. In the right eye, bulbar conjunctiva in supranasal quadrant polypoidal appearance was seen and there was subconjunctival cystic nodular mass in the superior conjunctival fornix. Systemic examination was unremarkable. Microbiological and histopathological examination of excision biopsy of the subconjunctival cyst revealed a granulomatous inflammation but acid fast bacilli was negative. Tissue sample was subjected to CBNAAT (Cartridge based nucleic acid amplification technique) examination in which mycobacterium tuberculosis was detected and sensitive to rifampicin. Patient was started on anti tuberculosis treatment under NTEP (national tuberculosis elimination programme) and full remission was achieved with 6 months of anti tuberculosis treatment. Although primary tuberculous conjunctivitis is a very rare condition, it should be considered in the differential diagnosis of treatment-resistant unilateral conjunctivitis. For definitive diagnosis, microbiological, histopathological and molecular examinations should be performed in conjunctival samples.

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“…Most of the cases reported in recent decades have come from endemic regions; 3 , 4 however, there have been a few case reports from developed countries. 5 , 6 , 7 , 8 , 9 …”

Section: Discussionmentioning

confidence: 99%

“…Moreover, only 4 cases of conjunctival tuberculosis have been reported from the WHO European region in last 5 decades. 5 , 6 , 7 , 8 Three of the cases were diagnosed with primary conjunctival tuberculosis. Interestingly, these three cases were health professionals (general practitioner, microbiologist, and radiologist) who often encountered Mycobacterium tuberculosis and it was thought that the conjunctival lesions were probably due to direct inoculation of mycobacteria to the conjunctiva.…”

Section: Discussionmentioning

confidence: 99%

“… 2 In recent decades, only isolated case reports of conjunctival tuberculosis have been published. 3 , 4 , 5 , 6 , 7 , 8 , 9 Conjunctival involvement is usually through direct inoculation of the organism to the conjunctiva or with contagious spread. 1 , 2 Conjunctival lesions are generally accompanied by regional lymphadenopathy, but the association with pulmonary tuberculosis is rare.…”

Section: Introductionmentioning

confidence: 99%

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Primary Conjunctival Tuberculosis

Solmaz¹,

Önder²,

Demir³

et al. 2018

tjo

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A 12-year-old girl was referred to our clinic because of unilateral conjunctivitis not responding to treatment. In the left eye, lower bulbar and tarsal conjunctiva had a polypoidal appearance due to micronodules and there was a subconjunctival nodular mass in the inferior fornix. Systemic examination was unremarkable except for a left preauricular lymphadenopathy. Excision biopsy of the subconjunctival mass revealed a granulomatous inflammation with caseation necrosis, but acid-fast bacilli (AFB) was negative. Fine needle-aspiration biopsy of the preauricular lymph node was performed. In microbiological examination, both AFB and mycobacterial culture were positive. The isolated mycobacteria strains were identified as Mycobacterium tuberculosis complex and full remission was achieved with 6 months of anti-tuberculosis treatment. Although primary tuberculous conjunctivitis is a very rare condition, it should be considered in the differential diagnosis of treatment-resistant unilateral conjunctivitis. For definitive diagnosis, microbiological and histopathological examinations should be performed both in conjunctiva and regional lymph node.

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Chronic cicatrising conjunctivitis in a patient with hemifacial cutaneous tuberculosis

Cited by 6 publications

References 6 publications

Orbital and external ocular manifestations of Mycobacterium tuberculosis: A review of the literature

Orbital and external ocular manifestations of Mycobacterium tuberculosis: A review of the literature

Primary Conjunctival Tuberculosis: A Case Report

Primary Conjunctival Tuberculosis

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