Chronic calcifying pancreatitis in rheumatic diseases.

Hortas, C.; Heras, G. de las; Lopez-Arias, M. J.; Martín, Luis Ángel Guerras; Pons‐Romero, F.

doi:10.1136/ard.54.1.77

Cited by 9 publications

(5 citation statements)

References 13 publications

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“…In the case reported by Hortas et al [ 6 ], two years elapsed between the first episode of pancreatitis and the appearance of findings of chronic disease; this situation is similar to the present case.…”

Section: Discussionsupporting

confidence: 90%

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Chronic Pancreatitis and Systemic Lupus Erythematosus: An Uncommon Association

Gutiérrez¹,

Casas²,

Cremaschi

et al. 2008

Case Rep Gastroenterol

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Section: Discussionsupporting

confidence: 90%

“…The association between SLE and CP is extremely rare. Up to now, only six cases have been reported in the English literature [ 5 , 6 , 7 , 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Chronic Pancreatitis and Systemic Lupus Erythematosus: An Uncommon Association

Gutiérrez¹,

Casas²,

Cremaschi

et al. 2008

Case Rep Gastroenterol

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“…The rate of pancreatitis in patients with SLE varies depending on individual series from Europe and the United States between 0.7 and 4% (3,4). This association is mainly at the expense of acute episodes of pancreatitis; however only four reports have been published regarding this relationship with chronic pancreatitis (5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

Pancreatitis and systemic lupus erythematosus

Noia

García

Rı́os

et al. 2009

Rev. esp. enferm. dig.

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Gastrointestinal symptoms in patients with SLE are common, specifically abdominal pain. However, the rate of pancreatic diseases is much lower and does not reach 5% according to published series in Europe and the USA. This association between SLE and pancreatic disease is basically at the expense of episodes of acute pancreatitis. An association with chronic pancreatitis is much more uncommon, and only four articles have been published showing this relationship.Three cases of SLE-associated pancreatitis are described, and disease onset, etiological factors, and clinical progression are analyzed. A review of the literature and a brief discussion about pathophysiological mechanisms and the role of corticosteroids are also included.Key words: Systemic lupus erythematosus. Acute pancreatitis. Chronic pancreatitis. INTRODUCTIONSince the first association between systemic lupus erythematosus (SLE) and pancreatitis was documented by Reifenstein et al. in 1939 (1), very few reports about the prevalence of pancreatic diseases in this rheumatologic disorder have been reported.Gastrointestinal symptoms in patients with SLE are common, specifically abdominal pain; as described in some series, it has been shown to have a prevalence of 19.2% (2). The rate of pancreatitis in patients with SLE varies depending on individual series from Europe and the United States between 0.7 and 4% (3,4). This association is mainly at the expense of acute episodes of pancreatitis; however only four reports have been published regarding this relationship with chronic pancreatitis (5-7).Three cases of SLE-associated pancreatitis are described, and disease onset, etiological factors and clinical progression are analyzed. A review of the literature and a brief discussion about the pathophysiological mechanisms and the role of corticosteroids are also included. METHODSA retrospective review of hospital admissions at Gastroenterology Department, University Hospital, Santiago de Compostela during 2001-2005 with the dual diagnosis of systemic lupus erythematosus and pancreatitis was made. Demographic data, clinical intervention, and progression parameters of pancreatic disease were identified. These patients were collected by searching our institution's computer database using the key words "pancreatitis" and "SLE". Demographic information registered from the medical charts included subject age, gender, time (years) from the initial diagnosis of SLE, alcohol abuse, medications, specially corticosteroids, and criteria used for SLE diagnosis.Clinical data collected included symptoms, SLE activity with a list of organs or systems involved, initial pancreatic enzymes, number of admissions for pancreatitis, and serologies for antinuclear antibodies (ANA) and C-reactive protein levels. All radiological results were documented, including abdominal ultrasounds, helical CT, cholangiopancreatic resonance (MRPC), endoscopic retrograde cholangiopancreatography (ERPC), and endoscopic ultrasounds (EUS

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“…Chronic pancreatitis associated with systemic lupus erythematosus (SLE) is limited to a few case reports [4][5][6][7] and represents a rare finding. In an analysis on 136 patients with SLE,10 patients with clinical or subclinical pancreatitis were identified [8].…”

Section: Discussionmentioning

confidence: 99%