Chronic Beneficial Effects of Type 1 Angiotensin II Receptor Antagonist in Patients with Chronic Hypoxemic Pulmonary Diseases

The Combined Use of Losartan and Muscle-Derived Stem Cells Significantly Improves the Functional Recovery of Muscle in a Young Mouse Model of Contusion Injuries

“…The mice received an average dose of 10 mg/kg/d, which is equivalent to the recommended therapeutic dose for the prevention of fibrous scar tissue deposition at the site of the muscle contusion in mice. 40 Dosing regimens were calculated according to the average body weight and daily fluid intake of the mice. 2,27,48 All animals were caged separately and allowed access to drinking water ad libitum with or without the addition of dissolved losartan from the time of injury to sacrifice.…”