Chronic ankle instability is associated with proprioception deficits: A systematic review and meta-analysis

Xue, Xiao’ao; Ma, Tengjia; Li, Qianru; Song, Yujie; Hua, Yinghui

doi:10.1016/j.jshs.2020.09.014

Cited by 75 publications

(82 citation statements)

References 69 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous researchers have primarily reported on proprioception deficits in CAI [5][6][7] and less on superficial sensory disorders [8]. The CPT tests directly stimulated and tested the different subgroups of sensory nerve fibres.…”

Section: Discussionmentioning

confidence: 99%

“…Notably, the injured and uninjured sides showed increased CPT values under 250-Hz and 5-Hz stimuli in our study, and these bilateral changes may reflect inherent differences or changes after injury via central modulation. Previous studies have reported bilateral changes after unilateral ankle sprain and CAI [ 7 , 23 ]. Sousa et al [ 32 ] reported bilateral deficits in proprioception in the injured and uninjured limbs of CAI patients.…”

Section: Discussionmentioning

confidence: 99%

“…Cho et al [ 6 ] used an isokinetic test and showed decreased joint position sensation in CAI participants. A systematic review reported that proprioception of the injured ankle in patients with CAI was impaired compared with that of the uninjured contralateral limb and in healthy people [ 7 ]. The superficial sensory test has been less studied in CAI.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Current perception threshold testing in chronic ankle instability

Zhang

Chen

et al. 2021

BMC Musculoskelet Disord

View full text Add to dashboard Cite

Background Damage to sensory input is an underlying pathology of chronic ankle instability (CAI). Therefore, it is necessary to evaluate the sensory function of patients with CAI. The present study quantitatively evaluated sensory nerve function in patients with CAI and healthy controls using current perception threshold (CPT) measurements, as well as the influence of sex, age, and body mass index (BMI) on CPT values and the relations between CPT frequencies. Methods Fifty-nine subjects with CAI and 30 healthy controls participated in this study. CPT values at the anterior talofibular ligament region were recorded on the injured and uninjured sides in CAI patients and on both sides in the healthy control group. Between group differences were compared. The influence of sex, age and BMI on CPT values was evaluated. Correlations between different frequencies were also studied. Results There were no significant differences in age, sex, height, weight or BMI between the CAI and healthy control groups. The CPT values did not show a significant difference by sex. The CPT values did not significantly correlate with age or BMI. Compared to the control group, the CAI group had significantly higher CPT values on the injured and uninjured sides under 250-Hz and 5-Hz electrical stimuli; the difference between the groups was significant (p < 0.01), and the effect size were large. No significant difference was observed under 2000-Hz stimuli. There were correlations between CPT values at different frequencies (p < 0.01), especially 250 Hz and 5 Hz. Conclusion The present study revealed increased sensory thresholds in 250-Hz- and 5-Hz-related sensory nerve fibres in the injured and uninjured ankles of patients with CAI. This increase may indicate dysfunction of A-delta and C fibres. Sex, age and BMI did not significantly impact CPT values. There were correlations between CPT values at different frequencies, especially 250 Hz and 5 Hz. Level of evidence Level III, case-control study.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Current perception threshold testing in chronic ankle instability

Zhang

Chen

et al. 2021

BMC Musculoskelet Disord

View full text Add to dashboard Cite

show abstract

“…The rates of recurrence, the condition of symptoms, and the rising cost of evaluation and management alarm physicians, as more ef icient methods, for diagnosis and treatment are explored. Because ankle sprains are common, and disabling to athletes, healthcare professionals must be able to implement the most current and evidence supported treatment strategies to ensure safe and rapid return to play [30][31][32]34,35,38].…”

Section: Discussionmentioning

confidence: 99%

“…When appropriately performed, protection and rehabilitation practices enhance the remodeling and inal maturation phases of soft tissue healing that typically require between 8 weeks to six months. In turn, the athlete will be ready to return to sport activity with full neuromuscular control, stability and strength [30][31][32]34,35].…”

Section: Preventionmentioning

confidence: 99%

The epidemiology, evaluation, and assessment of lateral ankle sprains in athletes

Cavazos¹,

Harkless²

2021

J Sports Med Ther

View full text Add to dashboard Cite

Approximately 30,000 ankle injuries occur every day in the United States. With the incidence estimated at more than 3 million a year and at a rate of 2.15/1,000 in the U.S. alone, medical specialists and other healthcare providers caring for the foot and ankle must take notice. Despite the millions of ankle injuries sustained annually, the true incidence may be underestimated, as fewer than half of individuals with ankle sprains seek medical attention from healthcare professionals. The economic burden associated with the evaluation, diagnosis, and treatment is close to $4 billion annually. Ankle sprains account for half of all sports injuries and remains a difficult diagnostic and therapeutic challenge in the athlete. Accurate diagnosis is critical as 40% of ankle sprains are misdiagnosed or poorly treated leading to chronic ankle pain and disability. Implementing evidence supported diagnostic and treatment strategies is the goal for ensuring safe and rapid return to play. The Lateral Ankle Sprain (LAS) is among the most common type of ankle sprains suffered during athletic activities. Up to 80% of LAS are of the inversion type, and 75% lead to recurrence and instability. Although most individuals experiencing a LAS return to activity within six weeks, many report continued pain, diminished function, and instability. The purpose of this review is to highlight the epidemiology, pathoetiology, pathoanatomy, and biomechanics of the LAS, enabling sports physicians to implement the best practice guidelines and protocols to manage this common enigma.

show abstract

Longitudinal neuroplasticity after ankle sprain in mice: A voxel‐based morphometry study on 11.7T MRI

Xue

Zhang

Tao

et al. 2022

Journal Orthopaedic Research

Self Cite

View full text Add to dashboard Cite

Lateral ankle sprains (LAS) might lead to joint sensory deafferentation, which induces maladaptive neuroplasticity, especially the morphological atrophy of the cerebellar vermis. However, longitudinal evidence on the causality of injury and neural differences is still lacking. To this end, this study aimed to determine whether the morphology of the central nervous system would be altered before and after ligament transection in LAS mouse models. A total of 40 C57BL/6 mice were randomly divided among the LAS, Sham and Blank groups. We repeatedly performed the balance beam test and neural voxel-based morphometry (VBM) measurements using an 11.7 T magnetic resonance imaging before and 2 months after the surgery.The results showed that for balance outcomes, the LAS group had a significantly longer time and more slips of the balance beam tests compared with the Sham and Blank groups at 2 months after surgery, with no significant difference among the three groups before surgery. Regarding the VBM analysis, the LAS group showed significantly lower VBM values in the central lobule III of the cerebellar vermis and medial amygdalar nucleus (MEA) compared with the Sham and Blank groups after surgery, with no significant difference among the three groups before surgery. In conclusion, lateral ligament injuries might lead to morphological atrophy of the cerebellar vermis in animal models, which might pave the way for the pathological process of ankle instability after LAS.

show abstract

Chronic ankle instability is associated with proprioception deficits: A systematic review and meta-analysis

Cited by 75 publications

References 69 publications

Current perception threshold testing in chronic ankle instability

Current perception threshold testing in chronic ankle instability

The epidemiology, evaluation, and assessment of lateral ankle sprains in athletes

Longitudinal neuroplasticity after ankle sprain in mice: A voxel‐based morphometry study on 11.7T MRI

Contact Info

Product

Resources

About