Chronic actinic dermatitis in a young patient with atopic dermatitis

Kurumaji, Yuko; Kondo, Seiji; Fukuro, Shuhei; Keong, Chin-Huai; Nishioka, Kiyoshi

doi:10.1016/s0190-9622(08)81736-7

Cited by 17 publications

(11 citation statements)

References 8 publications

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“…Chronic actinic dermatitis is an acquired, persistent eczematous photosensitivity eruption showing decreased MEDs for UVB and/or UVA and abnormal skin reactions to a wide range of wavelengths. The disease sometimes arises in association with preexisting eczematous disorders including atopic dermatitis [7, 8, 9]. In our study, 5 patients showed decreased MEDs for UVB radiation with abnormal, papular reactions (table 2).…”

Section: Discussionmentioning

confidence: 49%

Sun Exposure Is an Aggravating Factor Responsible for the Recalcitrant Facial Erythema in Adult Patients with Atopic Dermatitis

et al. 2002

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Background: In Japan, a considerable number of adult patients with atopic dermatitis suffer from recalcitrant facial erythema that resists common treatment with topical corticosteroids and antihistamines. Objective: Our purpose was to investigate the potential role of sun exposure in the aggravation of these facial lesions. Methods: The history of photoaggravation was taken from 74 adult patients with atopic dermatitis who suffered from recalcitrant facial erythema. Repeated UVB and UVA phototests were performed in 36 patients. Surface markers of infiltrating cells in UVB-provoked lesions were characterized immunohistochemically. Results: Forty-one of 74 patients experienced an exacerbation of the facial lesions after sun exposure. UVB testing revealed an abnormal, papular response in 14 of 36 patients. All of the 14 patients complained of clinical aggravation after sun exposure. No abnormal reactions were observed at UVA testing. In UVB-provoked lesions, CD4+ cells were predominant to CD8+ cells. Conclusion: Exposure to UVB radiation may be responsible for the recalcitrant facial erythema in at least some of the patients with atopic dermatitis.

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Section: Discussionmentioning

confidence: 49%

Sun Exposure Is an Aggravating Factor Responsible for the Recalcitrant Facial Erythema in Adult Patients with Atopic Dermatitis

et al. 2002

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“…However, this possibility does not seem to exclude the existence of CAD at a young age. [23,25,26,34] 17% 17% 67% UVB UVA UVB + A Fig. 4.…”

Section: Discussionmentioning

confidence: 99%

Throwing a Light on Photosensitivity in Atopic Dermatitis

Berge

Weelden

Bruijnzeel-Koomen

et al. 2009

American Journal of Clinical Dermatology

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“…People of all skin types, including those with black skin, can be affected (12–14). Although more common in elderly men, young patients of both sexes can be affected (14–17). In general, when it presents in those less than 40 years old, it supervenes on preexisting atopic dermatitis.…”

Section: Clinical Presentationmentioning

confidence: 99%

Diagnosis and treatment of chronic actinic dermatitis

Dawe

Ferguson

2003

Dermatol Ther

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Chronic actinic dermatitis, synonymous with the photosensitivity dermatitis and actinic reticuloid syndrome, presents as a dermatitis and/or a pseudolymphomatous eruption. Abnormal photosensitivity to ultraviolet (UV) and often visible radiation is a feature. Many patients also have multiple contact allergens. Histopathologic features vary, with a spectrum from mild dermatitis to pseudolymphomatous (reticuloid) features. The essential tests to make the diagnosis and to guide advice on avoidance of the responsible wavelengths and any contact allergens are phototesting and patch testing. Chronic actinic dermatitis can be regarded as a disorder of increased susceptibility, for reasons that remain uncertain, to develop delayed-type allergic responses to both endogenous photoallergens and exogenous allergens. Treatment consists of detailed advice on sunlight and allergen avoidance (guided by the results of investigations), topical corticosteroids, and emollients. When these measures are insufficient alone, systemic immunosuppressives may be considered: systemic prednisolone for acute exacerbations or azathioprine if systemic treatment is required for more than a few weeks.

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Chronic actinic dermatitis in a young patient with atopic dermatitis

Cited by 17 publications

References 8 publications

Sun Exposure Is an Aggravating Factor Responsible for the Recalcitrant Facial Erythema in Adult Patients with Atopic Dermatitis

Sun Exposure Is an Aggravating Factor Responsible for the Recalcitrant Facial Erythema in Adult Patients with Atopic Dermatitis

Throwing a Light on Photosensitivity in Atopic Dermatitis

Diagnosis and treatment of chronic actinic dermatitis

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