Chromosome aberration and environmental physical activity: Down syndrome and solar and cosmic ray activity, Israel, 1990–2000

Abstract

The possibility that environmental effects are associated with chromosome aberrations and various congenital pathologies has been discussed previously. Recent advances in the collection and computerization of data make studying these potential associations more feasible. The aim of this study was to investigate a possible link between the number of Down syndrome (DS) cases detected prenatally or at birth yearly in Israel over a 10-year period compared with the levels of solar and cosmic ray activity 1 year before the detection or birth of each affected child. Information about 1,108,449 births was collected for the years 1990-2000, excluding 1991, when data were unavailable. A total of 1,310 cases of DS were detected prenatally or at birth--138 in the non-Jewish community and 1,172 in the Jewish population. Solar activity indices--sunspot number and solar radio flux 2,800 MHz at 10.7 cm wavelength for 1989-1999--were compared with the number of DS cases detected. Pearson correlation coefficients (r) and their probabilities (P) were established for the percentage of DS cases in the whole population. There was a significant inverse correlation between the indices of solar activity and the number of cases of DS detected--r=-0.78, P=0.008 for sunspot number and r=-0.76, P=0.01 for solar flux. The possibility that cosmophysical factors inversely related to solar activity play a role in the pathogenesis of chromosome aberrations should be considered. We have confirmed a strong trend towards an association between the cosmic ray activity level and the incidence of DS.

Clinical cosmobiology: distribution of deaths during 180 months and cosmophysical activity. The Lithuanian study, 1990–2004 The role of cosmic rays

“…The number of ischemic stroke-related deaths is rising (26). We mentioned analogical changes for prolactin and 17-ketosteroids (31,(41)(42)(43)(44)(45)(46)(47). It is also remarkable that stormy days of GMA are relatively rare -in the last 30 years, in the middle latitudes, 3.5-6.0% of days yearly (47).…”

“…In addition, possible effect of CRA on newborn development, some congenital anomalies related to chromosome aberration (Down syndrome) was shown in a recent publications (42).…”

“…On the other hand, growth hormone, 11-hydroketosteroids, cardiac arrhythmia, including atrial fibrillation of new origin, related to some 30% of ischemic strokes (CVA) due to cerebral embolism, ventricular tachycardia and fibrillation, the main background for sudden cardiac death, are rising at lowest GMA levels (41)(42)(43)(44)(45)(46)(47). Such multidirectional response of the human organism to environment can be connected with the absence of decisive links of many large groups (IHD, CVA) of pathology that include subgroups of events with opposite answers to changing physical parameters ( Table 1).…”

Reduced Solar Activity Favors Twin Maternities

“…Also, the mechanisms by which solar outflows might influence the processes involved in producing and/or eliminating multiple fetuses remain unknown. One possible explanation is that cosmic factors negatively influence gametes, blastocytes, and embryos (Stoupel et al, 2005(Stoupel et al, , 2007. Ultrasonographic monitoring shows that about 40% of spontaneous dizygotic twin pregnancies end in single births (Landy & Keith, 1998).…”

Acute myocardial infarction (AMI) in context with the paradigm―month of birth and longevity

“…3) Such physical factors like Time, Solar, Geomagnetic, Cosmic Ray (Neutron) activity are connected with timing of distribution such pathologies like Down Syndrome [26], Congenital Heart Disease [27,28] some forms of congenital failures [29], Cystic fibrosis [30] etc. 4) Solar and Geomagnetic fields are inverse related and serving natural shields against Cosmic Ray (highest known energies) (Neutron activity at the Earth surface in imp/min counted) damaging effects on our Planet, but at very high levels SA and GMA are also connected with many human pathologies [30][31][32][33][34][35].…”