Abstract:Despite surging interest in space travel in recent decades, the impacts of prolonged, elevated exposure to galactic cosmic radiation (GCR) on human health remain poorly understood. This form of ionizing radiation causes significant changes to biological systems including damage to DNA structure by altering epigenetic phenotype with emphasis on DNA methylation. Building on previous work by Kennedy et al. (2018), we evaluated spatial DNA methylation patterns triggered by high-LET (56Fe, 28Si) and low-LET (X rays… Show more
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