Chromium nanoparticles improve bone turnover regulation in rats fed a high-fat, low-fibre diet
Ewelina Cholewińska,
Przemysław Sołek,
Jerzy Juśkiewicz
et al.
Abstract:The aim of the study was to investigate the effect of returning to a balanced diet combined with chromium picolinate (CrPic) or chromium nanoparticles (CrNPs) supplementation at a pharmacologically relevant dose of 0.3 mg/kg body weight on the expression level of selected genes and bone turnover markers in the blood and bones of rats fed an obese diet. The results of the study showed that chronic intake of a high-fat obesogenic diet negatively affects bone turnover by impairing processes of both synthesis and … Show more
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