Chromatographic separation of simulants of nerve and blister agents by combining one‐ and two‐channel columns with different stationary phases

Abstract

A two-channel gas chromatography column and a single-channel column were made by deep reactive-ion etching technology. The two short columns were coated with different stationary phases, and then linked without a modulator. This is to aim at increasing the sample capacity and achieving a higher separation efficiency in complex environments. The results show that the capacity of the connected column is approximately 4 and 1.5 times larger than that of the single- and two-channel columns, respectively. The linked column was utilized to separate a six-component mixture, composed of three simulants of nerve and blister agents and three interfering vapors. The results demonstrate that the combined column has a remarkably higher separation efficiency than the individual columns, and an acceptable resolution is achieved although the total length of the linked column is only 1.5 m.

Temperature‐programmed multicapillary gas chromatograph microcolumn for the analysis of odorous sulfur pollutants

“…The eight‐capillary microcolumn based on a silicon‐on‐glass process, as shown in Supporting Information Figure S1, is 30 μm in width, 300 μm in depth, and 50 cm in length micromachined by a deep reactive‐ion etching technology . The detailed process of the microfabrication techniques is as follows.…”

MEMS-based column coated with reduced graphene oxide as stationary phase for gas chromatography

“…In this paper, instead of using traditional capillary GC columns, we utilized a MEMS-based column for this study, since the developing of micro GC devices and systems is our main research effort. [27][28][29] The MEMS-based columns were fabricated on a silicon wafer by deep silicon etching technique where reduced graphene oxide was immobilized onto the column wall through sol-gel-derived ZnO particles as a supporting layer between the RGO lm and the channel wall. The rough ZnO underlayer not only contained a high surface area for the bilayer lm structure to increase gas-stationary phase interaction but also provided an alternative way to coat the RGO lm from the as-purchased aqueous solution.…”

Chopper-modulated gas chromatography electroantennography enabled using high-temperature MEMS flow control device

“…For example, there has been increasing interest in the development of miniaturized GC (μGC) systems, which can provide rapid diagnosis of VOCs with low cost and low power consumption. A standalone μGC is realized using three miniaturized components: a microinjector/preconcentrator for sample introduction [6][7][8] , a microcolumn for VOC separation 9,10 and a detector for identifying the separated compounds [11][12][13] . Ever since its inception 14 , the majority of research in μGC has been directed toward the fabrication of the above-mentioned basic components 15 .…”