Chromatographic Fingerprinting of Sarasvata Churna-an Ayurvedic Polyherbal Formulation for Epilepsy

Kaushik, Rahul; Jain, Jainendra; Mazumder, Avijit

doi:10.7324/japs.2018.8413

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…In recent times, chromatographic fingerprinting is one of the most important and powerful techniques used to evaluate the quality of herbal drugs [ 41 ]. In 1991, chromatographic fingerprinting was accepted by WHO as a technique for the identification and consistency evaluation of the herbal drugs.…”

Section: Authentication Of Plant-derived Moleculesmentioning

confidence: 99%

Plant-derived natural products for drug discovery: current approaches and prospects

Nasim

Sandeep

Mohanty

2022

Nucleus

127

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Nature has abundant source of drugs that need to be identified/purified for use as essential biologics, either individually or in combination in the modern medical field. These drugs are divided into small bio-molecules, plant-made biologics, and a recently introduced third category known as phytopharmaceutical drugs. The development of phytopharmaceutical medicines is based on the ethnopharmacological approach, which relies on the traditional medicine system. The concept of ‘one-disease one-target drug’ is becoming less popular, and the use of plant extracts, fractions, and molecules is the new paradigm that holds promising scope to formulate appropriate drugs. This led to discovering a new concept known as polypharmacology, where natural products from varying sources can engage with multiple human physiology targets. This article summarizes different approaches for phytopharmaceutical drug development and discusses the progress in systems biology and computational tools for identifying drug targets. We review the existing drug delivery methods to facilitate the efficient delivery of drugs to the targets. In addition, we describe different analytical techniques for the authentication and fingerprinting of plant materials. Finally, we highlight the role of biopharming in developing plant-based biologics.

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Section: Authentication Of Plant-derived Moleculesmentioning

confidence: 99%