Chromatographic analysis of lignans

Willför, Stefan; Smeds, Annika; Holmbom, Bjarne

doi:10.1016/j.chroma.2005.11.054

Cited by 155 publications

(93 citation statements)

References 102 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The levels of major flaxseed phytoetrogens, SECO and MAT, found in this study corresponded with literature data (Willför et al 2006). Relatively higher levels of these biological active compounds were found in oil flax samples.…”

Section: Discussionsupporting

confidence: 77%

“…The reachest dietary source of lignans are flaxseeds, in which glycosides of secoisolariciresinol (SECO) (Figure 1) and matairesinol (MAT) (Figure 2) are the major components accompanied with traces of pinoresinol, lariciresinol and isolariciresinol (Sicilia et al 2003). The content of SECO in flaxseeds has been reported to vary from 2900 to 12 600 mg/kg, levels of MAT were found in range 5.5-58.6 mg/kg (Willför et al 2006). After ingestion, plant lignans are converted by the human intestinal bacteria to the enterodiol and enterolactone, known as mammalian lignans.…”

Section: Introductionmentioning

confidence: 99%

“…They were identified in woody tissues of trees already in the 19 th century. Several hundreds of lignans have been documented since then in cereals, oilseeds, nuts, legumes and fruits (Willför et al 2006).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Lignans in Flaxseed

Krajčová¹,

Schulzová²,

Hajšlová³

et al. 2009

Czech J. Food Sci.

View full text Add to dashboard Cite

Abstract:Lignans are phytoestrogens which are present in a wide variety of plants. Epidemiological studies indicate that phytoestrogen-rich diets reduce risk of various hormone-dependent cancers, heart disease, and osteroporosis. One of the reachest dietary sources of lignans are flaxseeds, with glycosides of secoisolariciresinol (SECO) and matairesinol (MAT) as the major components. In this study LC-MS/MS method for the determination of plant lignans SECO and MAT in flaxseed was developed for analysis of a wide range of samples: (i) nine cultivars of oil flax treated with two types of fertilisers containing humic acids and (ii) fibre flax cultivar Venica fertilized with preparations containing various amounts of zinc. The levels of major phytoestrogen, SECO, were in range 2312-6994 mg/kg in oil flax and 1570-3100 mg/kg in fibre flax. The content of MAT was significantly lower, ranging from 3 to 9 in oil flax and 7-27 mg/kg in fibre flax.

show abstract

Section: Discussionsupporting

confidence: 77%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Lignans in Flaxseed

Krajčová¹,

Schulzová²,

Hajšlová³

et al. 2009

Czech J. Food Sci.

View full text Add to dashboard Cite

show abstract

“…Many methods of lignan detection and quantification have been established (Slanina and Glatz 2004;Willför et al 2006). Recently, a combination of liquid chromatography and electrospray ionization mass spectrometry (LC-ESI-MS) has become a sensitive method for lignan analysis (Eklund et al 2008;).…”

mentioning

confidence: 99%

Simultaneous quantification of lignans in Arabidopsis thaliana by highly sensitive capillary liquid chromatography-electrospray ionization-ion trap mass spectrometry

Okazawa

Hori

Okumura

et al. 2011

Plant Biotechnology

View full text Add to dashboard Cite

“…Lignans are a group of secondary metabolites consisting of compounds containing two phenylpropanoid units linked by oxidative coupling between C-8 and C-8' in their structures (Willfor et al, 2006). Several biological activities, such as anti-tumoral, fungicide, and anti-viral actions, have been attributed to the presence of these compounds, (Ayres & Loike, 1990;Botta et al, 2001;Pan et al, 2009).…”

Section: Lignansmentioning

confidence: 99%