“…Cell culture and small molecule chemical inhibitors Nine Human GC cell lines (SGC7901, BGC823, MKN45, AGS, HGC-27, MKN28, MGC803, N87, and MFC), a human normal gastric epithelial cell line (GES-1), and HEK293T were all purchased from Cell Bank of the Typical Culture Preservation Committee, Chinese Academy of Sciences (Shanghai, China). MEF cells from Pias4+/+ and Pias4-/mice were generous gifts from Prof. Shuai Ke (University of California, Los Angeles, Los Angeles, CA, USA) 13 . SGC7901/BGC823-shNC and SGC7901/BGC823-shKDM5B cells were generated via infection of lentiviral vectors containing shRNA (shscramble and shKDM5B) and puromycin selection.…”