Chromatic detection of glucose using polymerization of diacetylene vesicle

Abstract

A polydiacetylene vesicle was used to fabricate glucose sensor, allowing feasible colorimetric detection. The vesicle was formed by sonication of 10,12‐pentacosadiynoic acid (PCDA). H2O2 formed by the reaction between glucose and glucose oxidase functioned as the initiator for the polymerization of PCDA in the presence of horseradish peroxidase. The solution turned blue after the polymerization of PCDA vesicle. Thus, the glucose concentration could be detected to the concentration level that turns the solution to blue. The ultraviolet absorbance of glucose solution was proportional to glucose concentration. The results of this study indicate that glucose concentration upto 1 mM can be detected by change in blue color by eyes. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46394.

The crystal engineering of radiation-sensitive diacetylene cocrystals and salts

“…which disrupts the conjugated backbone, causing reduced overlap of the p orbitals, resulting in a widening of the HOMO-LUMO energy gap and hence the polydiacetylene absorbing light at a higher energy. 12,26,27 The commercially important diacetylene, 10,12-pentacosadiynoic acid (PCDA, 1), is used to provide a colourimetric change in practical chemosensors, [28][29][30][31][32][33] biosensors, 24,[34][35][36] and dosimeters. [37][38][39][40] Although PCDA is somewhat photoreactive, further tuning of its photoresponse is of considerable interest, especially for radiation dosimetry applications.…”

Effect of ethanol on the color transition of the polydiacetylene vesicle of 10,12‐pentacosadiynoic acid for butylamine detection

“…Therefore, almost reported PDA systems have been conducted in water. Our previous studies on PDAs were also conducted with a vesicle system in water . During the time we designed the PDA studies, we had difficulty because the target compounds were not soluble in water.…”

A Polydiacetylene‐based Colorimetric Adenosine Triphosphate Sensor: A Molecular Protecting Approach

“…One meritorious feature of PDA is that it displays a brilliant color change (typically blue to red) in response to physical and chemical/biochemical stimuli 2–13 . Accordingly, this stimulus‐responsive property of PDA has been extensively used for the development of colorimetric sensors 2–30 …”